POU2F1 and NCOR2

  • Number of citations of the paper that reports this interaction (PubMedID 11134019)
  • 13
  • Data Source:
  • HPRD (in vivo, in vitro)

POU2F1

NCOR2

Description POU class 2 homeobox 1 nuclear receptor corepressor 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Asthma ( 31619474)
  • Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
  • Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444)
  • Diastolic blood pressure ( 30224653)
  • Liver enzyme levels ( 18940312)
  • Pre-treatment viral load in HIV-1 infection ( 31219150)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs) ( 23648065)
  • Clubfoot ( 24667120)
  • Cocaine dependence ( 23958962)
  • Cognitive performance ( 19734545)
  • Diastolic blood pressure ( 30224653)
  • Height ( 31562340)
  • Lung function (FEV1) ( 30061609)
  • Mosquito bite size ( 28199695)
  • Multiple sclerosis ( 31604244)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 49 interacting genes: APP AR BARD1 BRCA1 CEBPE CREB1 ESR1 FDXR HCFC1 HMGA1 HMGB2 HNF1A HOXB13 HOXC9 IRF9 LIFR MNAT1 MSX1 NCOR2 NFYA NPAT NR3C1 PARP1 PBX1 PGR PKNOX1 PLK3 POGZ POU2AF1 PRKACA PRKDC RARA RELA RXRA SNAPC4 SOX2 SP1 SP4 STAT5A STAT5B TBP THRA TLE4 TLE5 TLX2 TNF TXNRD1 VDR XRCC6 88 interacting genes: AHR AKT1 AP2M1 AR ARNT ATXN1 ATXN1L BCL6 C1D CBFA2T2 CDK2 CEBPB CEP63 CHUK CIR1 CNOT2 DDX20 E2F1 ESR1 ESR2 FOS FOXP1 H4C1 HDAC1 HDAC10 HDAC3 HDAC4 HDAC5 HDAC7 HNF4A INPP5K IRF5 JUN KLF5 MYBL2 MYOD1 NCOA3 NCOA6 NCOR1 NFE2L2 NFKB1 NFKBIA NFKBIB NFKBIE NR1D1 NR1H2 NR1H4 NR1I2 NR2F1 NR2F2 NR3C1 NR4A1 PIN1 PML POU2F1 PPARA PPARD PPARG RANBP9 RARA RARB RARG RBPJ RELA RUNX1 RUNX1T1 RXRA RXRG SAP30 SIN3A SKIL SNW1 SP1 SPEN SRF STAT5A STAT5B SUMO1 TBL1X THRA THRB TNIK TNIP2 UBE2I VDR YWHAE ZBTB16 ZBTB7A
Entrez ID 5451 9612
HPRD ID 01250 02910
Ensembl ID ENSG00000143190 ENSG00000196498
Uniprot IDs A0A024R8Y2 P14859 C9J0Q5 C9JE98 Q9Y618
PDB IDs 1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU 1KKQ 1R2B 1XC5 2GPV 2L5G 2LTP 2ODD 2RT5 3R29 3R2A 4A69 4OAR 5X8Q 5X8X 5ZOO 5ZOP 6A22 6IVX
Enriched GO Terms of Interacting Partners?
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