PRKDC and XRCC4

  • Number of citations of the paper that reports this interaction (PubMedID 9430729)
  • 49
  • Data Source:
  • HPRD (in vitro)

PRKDC

XRCC4

Description protein kinase, DNA-activated, catalytic subunit X-ray repair cross complementing 4
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Clozapine-induced agranulocytosis ( 25187353)
  • Diisocyanate-induced asthma ( 25918132)
  • Heel bone mineral density ( 30598549)
  • Osteoarthritis biomarkers ( 25057126)
  • Squamous cell lung carcinoma ( 28604730)
  • Type 2 diabetes ( 25760438)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • White matter integrity (fractional anisotropy) ( 29752348)
  • White matter integrity (mean diffusivity) ( 29752348)
Interacting Genes 89 interacting genes: ABL1 AICDA AKT1 AKT2 AP1B1 ATM ATRIP BRCA1 C1D CASP3 CCNB1 CHEK1 CHEK2 CHUK CIB1 CLK1 CTDP1 DCAF1 DCLRE1C E4F1 EIF2S2 EIF4EBP1 EP300 ERG FH GSK3A GSK3B GZMB H1-1 H1-2 H2AX HDAC3 HMGB1 HMGB2 HNRNPA1 HNRNPC HOXC4 HSF1 HSP90AA1 IKBKB ILF2 JUN KAT2A LIG4 LYN MAPK8 MBP MKNK1 MRE11 MTNR1B NBN NCF1 NCF2 NCF4 NCOA6 NR3C1 PARP1 PCNA PDX1 PGR POU2F1 PPP6C PPP6R1 PPP6R3 PRKCD RAD17 RASSF1 RBBP8 RPA1 RPA2 SGO1 SP1 SRF SUMO2 THRA THRB TOP1 TP53 TREX1 UBE2I USF1 WRN XPA XRCC4 XRCC5 XRCC6 YWHAG YWHAQ ZBTB7A 19 interacting genes: ACTN1 AHNAK APLF APTX ASTE1 BIN1 CAAP1 CALM1 CHD3 CSNK2A1 FAM9B GZMB IFFO1 LIG4 NBN NHEJ1 PNKP PRKDC VIM
Entrez ID 5591 7518
HPRD ID 02941 15951
Ensembl ID ENSG00000253729 ENSG00000152422
Uniprot IDs P78527 A0A024RAL0 A0A024RAP0 A0A024RAQ8 Q13426 Q7Z763
PDB IDs 5LUQ 5W1R 5Y3R 1FU1 1IK9 3II6 3MUD 3Q4F 3RWR 3SR2 3W03 4XA4 5CHX 5CJ0 5CJ4 5E50 5WJ7 5WLZ 6ABO
Enriched GO Terms of Interacting Partners?
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