PRKDC and XPA

  • Number of citations of the paper that reports this interaction (PubMedID 16540648)
  • 40
  • Data Source:
  • BioGRID (enzymatic study)
  • HPRD (in vitro)

PRKDC

XPA

Description protein kinase, DNA-activated, catalytic subunit XPA, DNA damage recognition and repair factor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Hypothyroidism ( 27182965)
  • Obesity-related traits ( 23251661)
  • Serum thyroid-stimulating hormone levels ( 24852370)
  • Thyroid cancer (Papillary, radiation-related) ( 20350937)
Interacting Genes 89 interacting genes: ABL1 AICDA AKT1 AKT2 AP1B1 ATM ATRIP BRCA1 C1D CASP3 CCNB1 CHEK1 CHEK2 CHUK CIB1 CLK1 CTDP1 DCAF1 DCLRE1C E4F1 EIF2S2 EIF4EBP1 EP300 ERG FH GSK3A GSK3B GZMB H1-1 H1-2 H2AX HDAC3 HMGB1 HMGB2 HNRNPA1 HNRNPC HOXC4 HSF1 HSP90AA1 IKBKB ILF2 JUN KAT2A LIG4 LYN MAPK8 MBP MKNK1 MRE11 MTNR1B NBN NCF1 NCF2 NCF4 NCOA6 NR3C1 PARP1 PCNA PDX1 PGR POU2F1 PPP6C PPP6R1 PPP6R3 PRKCD RAD17 RASSF1 RBBP8 RPA1 RPA2 SGO1 SP1 SRF SUMO2 THRA THRB TOP1 TP53 TREX1 UBE2I USF1 WRN XPA XRCC4 XRCC5 XRCC6 YWHAG YWHAQ ZBTB7A 25 interacting genes: AP2M1 ATM ATR DDB1 DDB2 ERCC1 ERCC4 ERCC6 GPN1 GTF2E2 GTF2H1 HERC2 MSH2 MSH3 NDEL1 PCNA PRKDC RASSF1 RHOU RPA1 RPA2 RPA4 TRIM27 XAB2 XPC
Entrez ID 5591 7507
HPRD ID 02941 02045
Ensembl ID ENSG00000253729 ENSG00000136936
Uniprot IDs P78527 P23025
PDB IDs 5LUQ 5W1R 5Y3R 1D4U 1XPA 2JNW 6J44 6RO4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?