POU2F1 and FDXR

Number of citations of the paper that reports this interaction (PubMedID 11096094)
14

Data Source:
HPRD (in vivo, in vitro)

		POU2F1	FDXR
Description		POU class 2 homeobox 1	ferredoxin reductase
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Endoplasmic Reticulum Intracellular Membrane-bounded Organelle RNA Polymerase II Transcription Factor Complex	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific DNA Binding	Ferredoxin-NADP+ Reductase Activity NADPH-adrenodoxin Reductase Activity Oxidoreductase Activity
	Biological Process	Cytokine-mediated Signaling Pathway Cell Differentiation SnRNA Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Generation Of Precursor Metabolites And Energy Steroid Biosynthetic Process C21-steroid Hormone Biosynthetic Process Ubiquinone Biosynthetic Process Cholesterol Metabolic Process Sterol Metabolic Process Oxidation-reduction Process
Pathways		Interleukin-4 and Interleukin-13 signaling RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter Estrogen-dependent gene expression	Pregnenolone biosynthesis Endogenous sterols Electron transport from NADPH to Ferredoxin Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)
Drugs			Flavin adenine dinucleotide 2'-Monophosphoadenosine 5'-Diphosphoribose
Diseases
GWAS		Asthma ( 31619474) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Diastolic blood pressure ( 30224653) Liver enzyme levels ( 18940312) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		49 interacting genes: APP AR BARD1 BRCA1 CEBPE CREB1 ESR1 FDXR HCFC1 HMGA1 HMGB2 HNF1A HOXB13 HOXC9 IRF9 LIFR MNAT1 MSX1 NCOR2 NFYA NPAT NR3C1 PARP1 PBX1 PGR PKNOX1 PLK3 POGZ POU2AF1 PRKACA PRKDC RARA RELA RXRA SNAPC4 SOX2 SP1 SP4 STAT5A STAT5B TBP THRA TLE4 TLE5 TLX2 TNF TXNRD1 VDR XRCC6	4 interacting genes: FDX1 FHIT MTNR1A POU2F1
Entrez ID		5451	2232
HPRD ID		01250	00060
Ensembl ID		ENSG00000143190	ENSG00000161513
Uniprot IDs		A0A024R8Y2 P14859	A0A0A0MSZ4 A0A0A0MT64 A0A0A0MTN9 A0A0A0MTR6 A0A0C4DFN8 A0A0C4DGN7 P22570
PDB IDs		1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU
Enriched GO Terms of Interacting Partners?
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