TTC19 and IHO1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TTC19	IHO1
Description		tetratricopeptide repeat domain 19	interactor of HORMAD1 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Centrosome Midbody Respiratory Chain	Condensed Nuclear Chromosome
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Mitotic Cytokinesis Mitochondrial Respiratory Chain Complex III Assembly Oxidation-reduction Process	DNA Recombination Synapsis Spermatogenesis Meiotic DNA Double-strand Break Formation Oogenesis Regulation Of Homologous Chromosome Segregation
Pathways
Drugs
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS
Interacting Genes		12 interacting genes: ATXN1 CCDC33 CHMP4A EIF4ENIF1 HPS6 IHO1 L3MBTL3 NAB2 REL SPRED1 UBA1 UPF3B	50 interacting genes: ABI2 AQP1 ARHGEF9 ATP6V0D1 BCL6 C1orf109 CARD9 CDC23 COX5B DGCR6 DVL2 DYNLL1 DYNLL2 EAF2 EFHC1 FAM124A FANCG FANCL FHL3 FKBP6 GLRX3 GOLGA2 GRAP2 GYS1 HEXIM2 HINFP IQUB KANK2 KLC3 LMO2 LONRF1 MRFAP1L1 MVP MYO15B NEK6 NGB POLR1C PRKAB2 RAD51D RUNX1T1 SDCBP SMARCB1 STK25 TNS2 TRIM42 TTC19 USP2 USP20 ZGPAT ZNF688
Entrez ID		54902	339834
HPRD ID		07899	14172
Ensembl ID		ENSG00000011295	ENSG00000173421
Uniprot IDs		A0A024RD83 Q6DKK2	B4DZP6 Q8IYA8
PDB IDs
Enriched GO Terms of Interacting Partners?
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