IHO1 and TTC19

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		IHO1	TTC19
Description		interactor of HORMAD1 1	tetratricopeptide repeat domain 19
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome	Mitochondrion Mitochondrial Inner Membrane Centrosome Midbody Respiratory Chain
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	DNA Recombination Synapsis Spermatogenesis Meiotic DNA Double-strand Break Formation Oogenesis Regulation Of Homologous Chromosome Segregation	Mitotic Cytokinesis Mitochondrial Respiratory Chain Complex III Assembly Oxidation-reduction Process
Pathways
Drugs
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS
Interacting Genes		50 interacting genes: ABI2 AQP1 ARHGEF9 ATP6V0D1 BCL6 C1orf109 CARD9 CDC23 COX5B DGCR6 DVL2 DYNLL1 DYNLL2 EAF2 EFHC1 FAM124A FANCG FANCL FHL3 FKBP6 GLRX3 GOLGA2 GRAP2 GYS1 HEXIM2 HINFP IQUB KANK2 KLC3 LMO2 LONRF1 MRFAP1L1 MVP MYO15B NEK6 NGB POLR1C PRKAB2 RAD51D RUNX1T1 SDCBP SMARCB1 STK25 TNS2 TRIM42 TTC19 USP2 USP20 ZGPAT ZNF688	12 interacting genes: ATXN1 CCDC33 CHMP4A EIF4ENIF1 HPS6 IHO1 L3MBTL3 NAB2 REL SPRED1 UBA1 UPF3B
Entrez ID		339834	54902
HPRD ID		14172	07899
Ensembl ID		ENSG00000173421	ENSG00000011295
Uniprot IDs		B4DZP6 Q8IYA8	A0A024RD83 Q6DKK2
PDB IDs
Enriched GO Terms of Interacting Partners?
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