TTC19 and HPS6

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		TTC19	HPS6
Description		tetratricopeptide repeat domain 19	HPS6 biogenesis of lysosomal organelles complex 2 subunit 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Centrosome Midbody Respiratory Chain	Lysosomal Membrane Endoplasmic Reticulum Membrane BLOC-2 Complex Early Endosome Membrane
	Molecular Function	Protein Binding	Protein Binding Rab GTPase Binding GTP-dependent Protein Binding
	Biological Process	Mitotic Cytokinesis Mitochondrial Respiratory Chain Complex III Assembly Oxidation-reduction Process	Organelle Organization Blood Coagulation Melanocyte Differentiation Lysosome Localization Protein Localization To Membrane
Pathways
Drugs
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome	Hermansky-Pudlak syndrome (HPS)
GWAS			Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435)
Interacting Genes		12 interacting genes: ATXN1 CCDC33 CHMP4A EIF4ENIF1 HPS6 IHO1 L3MBTL3 NAB2 REL SPRED1 UBA1 UPF3B	9 interacting genes: CREB1 EP300 HPS5 MARK4 MNAT1 OSGEP PIK3CB PUM3 TTC19
Entrez ID		54902	79803
HPRD ID		07899	08471
Ensembl ID		ENSG00000011295	ENSG00000166189
Uniprot IDs		A0A024RD83 Q6DKK2	Q86YV9
PDB IDs
Enriched GO Terms of Interacting Partners?
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