IHO1 and RUNX1T1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		IHO1	RUNX1T1
Description		interactor of HORMAD1 1	RUNX1 partner transcriptional co-repressor 1
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome	Nucleus Nucleoplasm Nuclear Matrix
	Molecular Function	Protein Binding	DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	DNA Recombination Synapsis Spermatogenesis Meiotic DNA Double-strand Break Formation Oogenesis Regulation Of Homologous Chromosome Segregation	Generation Of Precursor Metabolites And Energy Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases			Acute myeloid leukemia (AML)
GWAS			Chronotype ( 30696823) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549) Intelligence (MTAG) ( 29326435) Number of sexual partners ( 30643258) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Plasma anti-thyroglobulin levels ( 29678681) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		50 interacting genes: ABI2 AQP1 ARHGEF9 ATP6V0D1 BCL6 C1orf109 CARD9 CDC23 COX5B DGCR6 DVL2 DYNLL1 DYNLL2 EAF2 EFHC1 FAM124A FANCG FANCL FHL3 FKBP6 GLRX3 GOLGA2 GRAP2 GYS1 HEXIM2 HINFP IQUB KANK2 KLC3 LMO2 LONRF1 MRFAP1L1 MVP MYO15B NEK6 NGB POLR1C PRKAB2 RAD51D RUNX1T1 SDCBP SMARCB1 STK25 TNS2 TRIM42 TTC19 USP2 USP20 ZGPAT ZNF688	52 interacting genes: ABI3 ATN1 BCL6 BRCA1 C19orf57 CBFA2T3 CBY2 CEP170P1 CPSF7 CREB3L1 DNMT1 EFHC2 EPS8 ETS1 GFI1 GSE1 HDAC1 HDAC3 HDAC8 HOMER3 HSP90AA1 ID1 ID3 IHO1 KPNA1 KPNB1 LPXN LZTS2 MEOX2 MID2 NCOR1 NCOR2 NECAB2 NEUROG1 PCBD2 PRKAR2A SIN3A SPEN SPRY2 STX11 TAF9B TAL2 TCF12 TCF3 TCF4 TRIM42 UBQLN4 VDR WBP11 ZBTB16 ZMYM4 ZNF652
Entrez ID		339834	862
HPRD ID		14172	00590
Ensembl ID		ENSG00000173421	ENSG00000079102
Uniprot IDs		B4DZP6 Q8IYA8	A0A087WWT6 A0A0A0MSU1 B2R6I9 Q06455 W8FW32
PDB IDs			1WQ6 2DJ8 2H7B 2KNH 2KYG 2OD1 2ODD 2PP4 4JOL
Enriched GO Terms of Interacting Partners?
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