IHO1 and STK25

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		IHO1	STK25
Description		interactor of HORMAD1 1	serine/threonine kinase 25
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome	Golgi Membrane Cell Cytoplasm Golgi Apparatus Extracellular Exosome
	Molecular Function	Protein Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process	DNA Recombination Synapsis Spermatogenesis Meiotic DNA Double-strand Break Formation Oogenesis Regulation Of Homologous Chromosome Segregation	Protein Phosphorylation Response To Oxidative Stress Establishment Or Maintenance Of Cell Polarity Signal Transduction Regulation Of Mitotic Cell Cycle Signal Transduction By Protein Phosphorylation Stress-activated Protein Kinase Signaling Cascade Activation Of Protein Kinase Activity Positive Regulation Of Stress-activated MAPK Cascade Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Response To Hydrogen Peroxide Protein Autophosphorylation Positive Regulation Of Axonogenesis Golgi Localization Establishment Of Golgi Localization Golgi Reassembly
Pathways
Drugs
Diseases
GWAS			Medication use (thyroid preparations) ( 31015401) Prostate cancer ( 23535732) Vitiligo ( 27723757)
Interacting Genes		50 interacting genes: ABI2 AQP1 ARHGEF9 ATP6V0D1 BCL6 C1orf109 CARD9 CDC23 COX5B DGCR6 DVL2 DYNLL1 DYNLL2 EAF2 EFHC1 FAM124A FANCG FANCL FHL3 FKBP6 GLRX3 GOLGA2 GRAP2 GYS1 HEXIM2 HINFP IQUB KANK2 KLC3 LMO2 LONRF1 MRFAP1L1 MVP MYO15B NEK6 NGB POLR1C PRKAB2 RAD51D RUNX1T1 SDCBP SMARCB1 STK25 TNS2 TRIM42 TTC19 USP2 USP20 ZGPAT ZNF688	16 interacting genes: APP CCNDBP1 CEP70 GOLGA2 HDAC2 IHO1 IKBKG LRRK2 MFHAS1 MTDH NEDD4 PDCD10 TRIM27 UBE2D3 YWHAZ ZDHHC17
Entrez ID		339834	10494
HPRD ID		14172	03770
Ensembl ID		ENSG00000173421	ENSG00000115694
Uniprot IDs		B4DZP6 Q8IYA8	A0A024R4B2 A0A0S2Z4Y2 B3KRS6 B4DMA5 B4DVS7 B4E185 O00506 Q96BA2
PDB IDs			2XIK 3W8H 4NZW
Enriched GO Terms of Interacting Partners?
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