PBX3 and TPM3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PBX3	TPM3
Description		PBX homeobox 3	tropomyosin 3
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Transcription Factor Complex	Stress Fiber Cytosol Cytoskeleton Muscle Thin Filament Tropomyosin Actin Filament Actin Cytoskeleton Extracellular Exosome
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific	Molecular_function Protein Binding Actin Filament Binding
	Biological Process	Regulation Of Respiratory Gaseous Exchange By Neurological System Process Anterior Compartment Pattern Formation Posterior Compartment Specification Respiratory Gaseous Exchange Adult Locomotory Behavior Dorsal Spinal Cord Development Positive Regulation Of Transcription By RNA Polymerase II Neuron Development	Muscle Contraction Actin Filament Organization Muscle Filament Sliding
Pathways			Striated Muscle Contraction Smooth Muscle Contraction
Drugs			Phenethyl Isothiocyanate
Diseases			Congenital fiber type disproportion (CFTD) Cap myopathy Thyroid cancer Nemaline myopathy
GWAS		Dentures ( 31235808) Medication use (opioids) ( 31015401) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Pulse pressure ( 30578418) Response to mTOR inhibitor (everolimus) ( 24009623) Sleep duration ( 30531941) Squamous cell lung carcinoma ( 28604730) Systolic blood pressure ( 30224653 30578418)	Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Platelet count ( 27863252) Smoking initiation (ever regular vs never regular) ( 30679032)
Interacting Genes		15 interacting genes: AGTRAP ARL6IP1 CNTRL FSD2 HOXA9 HOXB8 MAGEA1 MAGEC2 MAL2 MEIS1 RABAC1 TPM3 TRAF1 TRIM44 ZNHIT3	44 interacting genes: ACTA1 ACTB BLOC1S6 C1orf216 CCDC102B CCDC114 CCDC146 CCHCR1 CNN1 DVL2 FAM9C FBXO5 HDDC3 HOOK2 HSF2 IFIT3 IKBIP KCNE1 KIFC3 KXD1 LCA5L LURAP1 MAD1L1 MAGEA11 NEK2 NOD2 OIP5 PBX3 S100A2 S100A4 SMAD3 SUMO4 SYCE1 TFPT THAP1 TLK1 TMOD1 TMOD2 TNNT1 TRAP1 TRIM27 TRIP6 VPS52 WASH3P
Entrez ID		5090	7170
HPRD ID		15938	01840
Ensembl ID		ENSG00000167081	ENSG00000143549
Uniprot IDs		P40426 Q5JS98 Q96AL5	A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4I4 B4DQ80 P06753
PDB IDs			6OTN
Enriched GO Terms of Interacting Partners?
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