TPM3 and BLOC1S6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TPM3	BLOC1S6
Description		tropomyosin 3	biogenesis of lysosomal organelles complex 1 subunit 6
Image			No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cytosol Cytoskeleton Muscle Thin Filament Tropomyosin Actin Filament Actin Cytoskeleton Extracellular Exosome	Cell Cytoplasm Cytosol Extrinsic Component Of Membrane Transport Vesicle BLOC-1 Complex SNARE Complex Presynapse Axon Cytoplasm
	Molecular Function	Molecular_function Protein Binding Actin Filament Binding	Protein Binding Syntaxin Binding Identical Protein Binding Protein Homodimerization Activity Actin Filament Binding
	Biological Process	Muscle Contraction Actin Filament Organization Muscle Filament Sliding	Anterograde Axonal Transport Synaptic Vesicle Docking Neuron Projection Development Melanosome Transport Melanosome Organization Endosome To Melanosome Transport Intracellular Transport Anterograde Synaptic Vesicle Transport Positive Regulation Of Pigment Cell Differentiation
Pathways		Striated Muscle Contraction Smooth Muscle Contraction	Golgi Associated Vesicle Biogenesis
Drugs		Phenethyl Isothiocyanate
Diseases		Congenital fiber type disproportion (CFTD) Cap myopathy Thyroid cancer Nemaline myopathy
GWAS		Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Platelet count ( 27863252) Smoking initiation (ever regular vs never regular) ( 30679032)
Interacting Genes		44 interacting genes: ACTA1 ACTB BLOC1S6 C1orf216 CCDC102B CCDC114 CCDC146 CCHCR1 CNN1 DVL2 FAM9C FBXO5 HDDC3 HOOK2 HSF2 IFIT3 IKBIP KCNE1 KIFC3 KXD1 LCA5L LURAP1 MAD1L1 MAGEA11 NEK2 NOD2 OIP5 PBX3 S100A2 S100A4 SMAD3 SUMO4 SYCE1 TFPT THAP1 TLK1 TMOD1 TMOD2 TNNT1 TRAP1 TRIM27 TRIP6 VPS52 WASH3P	38 interacting genes: ABI2 AGGF1 ANK1 APP BLOC1S1 BLOC1S2 BLOC1S4 CCDC136 CCDC22 CCHCR1 CDK5R1 CORO6 DCTN2 DTNBP1 EPS8 EXOC8 HAUS1 IFT20 KRT13 LURAP1 MED21 NDC80 NDN NTAQ1 NUP62 OLFM2 PLEKHA5 PLEKHF2 RABGEF1 SKA1 SLC4A1 SMN2 SNAPIN STX11 STX12 SYCE3 TPM3 WASHC3
Entrez ID		7170	26258
HPRD ID		01840	16055
Ensembl ID		ENSG00000143549	ENSG00000104164
Uniprot IDs		A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4I4 B4DQ80 P06753	B3KY40 H3BST1 Q9UL45
PDB IDs		6OTN
Enriched GO Terms of Interacting Partners?
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