TPM3 and TMOD1

Number of citations of the paper that reports this interaction (PubMedID 10871039)
18

Data Source:
HPRD (in vitro)

		TPM3	TMOD1
Description		tropomyosin 3	tropomodulin 1
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GO Annotations	Cellular Component	Stress Fiber Cytosol Cytoskeleton Muscle Thin Filament Tropomyosin Actin Filament Actin Cytoskeleton Extracellular Exosome	Cytosol Cytoskeleton Striated Muscle Thin Filament Actin Filament COP9 Signalosome Membrane Myofibril Sarcomere Cortical Cytoskeleton
	Molecular Function	Molecular_function Protein Binding Actin Filament Binding	Actin Binding Tropomyosin Binding Actin Filament Binding
	Biological Process	Muscle Contraction Actin Filament Organization Muscle Filament Sliding	Muscle Contraction Actin Filament Organization Adult Locomotory Behavior Muscle Filament Sliding Myofibril Assembly Pointed-end Actin Filament Capping Lens Fiber Cell Development
Pathways		Striated Muscle Contraction Smooth Muscle Contraction	Striated Muscle Contraction
Drugs		Phenethyl Isothiocyanate
Diseases		Congenital fiber type disproportion (CFTD) Cap myopathy Thyroid cancer Nemaline myopathy
GWAS		Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Platelet count ( 27863252) Smoking initiation (ever regular vs never regular) ( 30679032)	Barrett's esophagus ( 27527254) Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Intracranial aneurysm ( 30823506) Obesity-related traits ( 23251661) Thyroid cancer (Papillary, radiation-related) ( 20350937) Zinc levels ( 26025379)
Interacting Genes		44 interacting genes: ACTA1 ACTB BLOC1S6 C1orf216 CCDC102B CCDC114 CCDC146 CCHCR1 CNN1 DVL2 FAM9C FBXO5 HDDC3 HOOK2 HSF2 IFIT3 IKBIP KCNE1 KIFC3 KXD1 LCA5L LURAP1 MAD1L1 MAGEA11 NEK2 NOD2 OIP5 PBX3 S100A2 S100A4 SMAD3 SUMO4 SYCE1 TFPT THAP1 TLK1 TMOD1 TMOD2 TNNT1 TRAP1 TRIM27 TRIP6 VPS52 WASH3P	4 interacting genes: NEB PRKAA2 TMSB10 TPM3
Entrez ID		7170	7111
HPRD ID		01840	01838
Ensembl ID		ENSG00000143549	ENSG00000136842
Uniprot IDs		A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4I4 B4DQ80 P06753	P28289
PDB IDs		6OTN	4PKG 4PKH 4PKI 4Z8G 4Z94
Enriched GO Terms of Interacting Partners?
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