PBX3 and MAGEC2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PBX3	MAGEC2
Description		PBX homeobox 3	MAGE family member C2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Transcription Factor Complex	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Regulation Of Respiratory Gaseous Exchange By Neurological System Process Anterior Compartment Pattern Formation Posterior Compartment Specification Respiratory Gaseous Exchange Adult Locomotory Behavior Dorsal Spinal Cord Development Positive Regulation Of Transcription By RNA Polymerase II Neuron Development	Cellular Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity
Pathways
Drugs
Diseases
GWAS		Dentures ( 31235808) Medication use (opioids) ( 31015401) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Pulse pressure ( 30578418) Response to mTOR inhibitor (everolimus) ( 24009623) Sleep duration ( 30531941) Squamous cell lung carcinoma ( 28604730) Systolic blood pressure ( 30224653 30578418)	Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956) Non-response to bupropion and depression ( 27622933)
Interacting Genes		15 interacting genes: AGTRAP ARL6IP1 CNTRL FSD2 HOXA9 HOXB8 MAGEA1 MAGEC2 MAL2 MEIS1 RABAC1 TPM3 TRAF1 TRIM44 ZNHIT3	13 interacting genes: MNAT1 P4HA3 PBX3 PCGF6 RBX1 RNF166 SSX1 SSX2 TAF9 TRAF4 TRIM8 UBR3 ZMYND11
Entrez ID		5090	51438
HPRD ID		15938	06632
Ensembl ID		ENSG00000167081	ENSG00000046774
Uniprot IDs		P40426 Q5JS98 Q96AL5	Q9UBF1
PDB IDs
Enriched GO Terms of Interacting Partners?
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