TPM3 and HDDC3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		TPM3	HDDC3
Description		tropomyosin 3	HD domain containing 3
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GO Annotations	Cellular Component	Stress Fiber Cytosol Cytoskeleton Muscle Thin Filament Tropomyosin Actin Filament Actin Cytoskeleton Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding Actin Filament Binding	Protein Binding Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase Activity Metal Ion Binding
	Biological Process	Muscle Contraction Actin Filament Organization Muscle Filament Sliding
Pathways		Striated Muscle Contraction Smooth Muscle Contraction
Drugs		Phenethyl Isothiocyanate
Diseases		Congenital fiber type disproportion (CFTD) Cap myopathy Thyroid cancer Nemaline myopathy
GWAS		Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Platelet count ( 27863252) Smoking initiation (ever regular vs never regular) ( 30679032)
Interacting Genes		44 interacting genes: ACTA1 ACTB BLOC1S6 C1orf216 CCDC102B CCDC114 CCDC146 CCHCR1 CNN1 DVL2 FAM9C FBXO5 HDDC3 HOOK2 HSF2 IFIT3 IKBIP KCNE1 KIFC3 KXD1 LCA5L LURAP1 MAD1L1 MAGEA11 NEK2 NOD2 OIP5 PBX3 S100A2 S100A4 SMAD3 SUMO4 SYCE1 TFPT THAP1 TLK1 TMOD1 TMOD2 TNNT1 TRAP1 TRIM27 TRIP6 VPS52 WASH3P	10 interacting genes: APP CCDC172 CEP57L1 EXOC5 GKAP1 GOLGA8EP GOLGA8F NMI TNIP1 TPM3
Entrez ID		7170	374659
HPRD ID		01840	14635
Ensembl ID		ENSG00000143549	ENSG00000184508
Uniprot IDs		A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4I4 B4DQ80 P06753	Q8N4P3
PDB IDs		6OTN	3NR1 5VXA
Enriched GO Terms of Interacting Partners?
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