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ITGB1 and EPS8
Number of citations of the paper that reports this interaction (PubMedID
12606711
)
115
Data Source:
HPRD
(in vitro)
ITGB1
EPS8
Description
integrin subunit beta 1
epidermal growth factor receptor pathway substrate 8
Image
GO Annotations
Cellular Component
Ruffle
Cell
Cytoplasm
Plasma Membrane
Focal Adhesion
Integrin Complex
External Side Of Plasma Membrane
Cell Surface
Intercalated Disc
Membrane
Lamellipodium
Filopodium
Neuromuscular Junction
Cleavage Furrow
Ruffle Membrane
Protein-containing Complex
Integrin Alpha1-beta1 Complex
Integrin Alpha2-beta1 Complex
Integrin Alpha3-beta1 Complex
Integrin Alpha5-beta1 Complex
Integrin Alpha7-beta1 Complex
Integrin Alpha8-beta1 Complex
Integrin Alpha10-beta1 Complex
Integrin Alpha11-beta1 Complex
Myelin Sheath Abaxonal Region
Sarcolemma
Melanosome
Dendritic Spine
Receptor Complex
Membrane Raft
Perinuclear Region Of Cytoplasm
Recycling Endosome
Extracellular Exosome
Invadopodium Membrane
Glial Cell Projection
Schaffer Collateral - CA1 Synapse
Glutamatergic Synapse
Integral Component Of Synaptic Membrane
Plasma Membrane
Brush Border
Cell Cortex
Postsynaptic Density
NMDA Selective Glutamate Receptor Complex
Cell Junction
Growth Cone
Vesicle
Stereocilium
Stereocilium Tip
Ruffle Membrane
Extracellular Exosome
Glutamatergic Synapse
Molecular Function
Virus Receptor Activity
Fibronectin Binding
Protease Binding
Actin Binding
Integrin Binding
Protein Binding
Coreceptor Activity
C-X3-C Chemokine Binding
Laminin Binding
Protein-containing Complex Binding
Cadherin Binding
Metal Ion Binding
Protein Heterodimerization Activity
Cell Adhesion Molecule Binding
Collagen Binding Involved In Cell-matrix Adhesion
Protein Tyrosine Kinase Binding
Actin Binding
Protein Binding
Rac Guanyl-nucleotide Exchange Factor Activity
Signaling Adaptor Activity
Rac GTPase Binding
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Establishment Of Mitotic Spindle Orientation
In Utero Embryonic Development
Cell Fate Specification
Cell Migration Involved In Sprouting Angiogenesis
Phagocytosis
Cellular Defense Response
Cell Adhesion
Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Leukocyte Cell-cell Adhesion
Cell-matrix Adhesion
Calcium-independent Cell-matrix Adhesion
Transforming Growth Factor Beta Receptor Signaling Pathway
Integrin-mediated Signaling Pathway
Positive Regulation Of Cell Proliferation
Germ Cell Migration
Visual Learning
Regulation Of Collagen Catabolic Process
Positive Regulation Of Fibroblast Migration
Cell Migration
Cytokine-mediated Signaling Pathway
Formation Of Radial Glial Scaffolds
CD40 Signaling Pathway
Cell Projection Organization
Lamellipodium Assembly
B Cell Differentiation
Extracellular Matrix Organization
Positive Regulation Of Cell Migration
Cell-substrate Adhesion
Receptor Internalization
Cell Adhesion Mediated By Integrin
Cell-cell Adhesion Mediated By Integrin
Heterotypic Cell-cell Adhesion
Negative Regulation Of Rho Protein Signal Transduction
Positive Regulation Of Apoptotic Process
Stress Fiber Assembly
Positive Regulation Of GTPase Activity
Sarcomere Organization
Negative Regulation Of Cell Differentiation
Positive Regulation Of Angiogenesis
Viral Entry Into Host Cell
Mesodermal Cell Differentiation
Axon Extension
Dendrite Morphogenesis
Regulation Of Immune Response
Modulation Of Chemical Synaptic Transmission
Leukocyte Migration
Leukocyte Tethering Or Rolling
Regulation Of Cell Cycle
Positive Regulation Of Protein Kinase B Signaling
Cardiac Muscle Cell Differentiation
Cellular Response To Low-density Lipoprotein Particle Stimulus
Basement Membrane Organization
Positive Regulation Of Wound Healing
Positive Regulation Of Protein Localization To Plasma Membrane
Positive Regulation Of Signaling Receptor Activity
Negative Regulation Of Anoikis
Rho Protein Signal Transduction
Adult Locomotory Behavior
Regulation Of Cell Shape
Positive Regulation Of Signal Transduction
Exit From Mitosis
Rac Protein Signal Transduction
Regulation Of Actin Filament Length
Actin Cytoskeleton Reorganization
Regulation Of Rho Protein Signal Transduction
Dendritic Cell Migration
Behavioral Response To Ethanol
Barbed-end Actin Filament Capping
Actin Filament Bundle Assembly
Actin Crosslink Formation
Actin Polymerization-dependent Cell Motility
Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels
Positive Regulation Of Ruffle Assembly
Cellular Response To Leukemia Inhibitory Factor
Pathways
Elastic fibre formation
Fibronectin matrix formation
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Cell surface interactions at the vascular wall
Basigin interactions
Molecules associated with elastic fibres
Integrin cell surface interactions
Integrin cell surface interactions
Laminin interactions
Laminin interactions
Syndecan interactions
ECM proteoglycans
Other semaphorin interactions
Signal transduction by L1
Localization of the PINCH-ILK-PARVIN complex to focal adhesions
CHL1 interactions
RHO GTPases Activate Formins
Interleukin-4 and Interleukin-13 signaling
Platelet Adhesion to exposed collagen
MET activates PTK2 signaling
MET interacts with TNS proteins
HCMV Early Events
Drugs
Antithymocyte immunoglobulin (rabbit)
Diseases
GWAS
Depression (quantitative trait) (
20800221
)
Suicide in bipolar disorder (
25917933
)
Metabolite levels (
23823483
)
Protein quantitative trait loci (
18464913
)
Interacting Genes
78 interacting genes:
ACAP1
ACTN1
ACTN4
ARHGAP5
CANX
CD151
CD36
CD46
CD82
CD9
CRKL
DAG1
DOK1
EFNA4
EGFR
EPS8
FBLN1
FBXO2
FERMT1
FERMT2
FERMT3
FHL2
FLNA
FLNB
FLT4
FN1
HSPD1
HSPG2
ICAM4
IGF1R
ILK
ITGA1
ITGA10
ITGA11
ITGA2
ITGA3
ITGA4
ITGA5
ITGA6
ITGA8
ITGA9
ITGAV
ITGB1BP1
ITGB1BP2
LAMA1
LGALS1
LGALS3BP
LGALS8
MAP4K4
MET
NCKIPSD
NF2
NME1
NMRK2
PDHB
PIP5K1C
PLAUR
PRKCA
PRKCE
PTK2
PXN
RAB25
RACK1
SLC3A2
SPP1
TGFBR1
TGM2
TGOLN2
TIMP2
TLN1
TNC
TSPAN4
UPF2
VCAM1
VCAN
YWHAB
ZEB1
ZNF33A
61 interacting genes:
ABI1
ACTA1
ADAM22
AIMP2
ALDH7A1
ARMC1
BAIAP2
BCKDK
BLOC1S6
BORCS6
BYSL
C19orf25
C6orf141
C8orf33
CASK
CBL
CCDC85B
CSNK2B
CTNNA3
CXCL2
DNALI1
DVL1
EGFR
GOLGA8EP
GRB2
GULP1
HNRNPC
HOOK2
INPP5J
ITGB1
ITGB3
ITGB5
ITSN2
MAP1LC3B
MAP3K11
MRPL20
MYO15A
NACC2
NFKB2
PCM1
PROSER2
RCAN3
RFXAP
RSPH14
RUNX1T1
SCRN3
SERPINA5
SF3B3
SHB
SHC1
SLC27A4
SMARCE1
SOS1
SRC
TDP2
TEX28
TPRN
USP6NL
XAGE2
XRCC6
ZZZ3
Entrez ID
3688
2059
HPRD ID
00628
02563
Ensembl ID
ENSG00000150093
ENSG00000151491
Uniprot IDs
P05556
B4E3T6
Q12929
PDB IDs
1K11
1LHA
3G9W
3T9K
3VI3
3VI4
4DX9
4WJK
4WK0
4WK2
4WK4
2E8M
Enriched GO Terms of Interacting Partners
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