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ITGB1 and ACTN1
Number of citations of the paper that reports this interaction (PubMedID
2116421
)
190
Data Source:
BioGRID
(pull down)
ITGB1
ACTN1
Description
integrin subunit beta 1
actinin alpha 1
Image
GO Annotations
Cellular Component
Ruffle
Cell
Cytoplasm
Plasma Membrane
Focal Adhesion
Integrin Complex
External Side Of Plasma Membrane
Cell Surface
Intercalated Disc
Membrane
Lamellipodium
Filopodium
Neuromuscular Junction
Cleavage Furrow
Ruffle Membrane
Protein-containing Complex
Integrin Alpha1-beta1 Complex
Integrin Alpha2-beta1 Complex
Integrin Alpha3-beta1 Complex
Integrin Alpha5-beta1 Complex
Integrin Alpha7-beta1 Complex
Integrin Alpha8-beta1 Complex
Integrin Alpha10-beta1 Complex
Integrin Alpha11-beta1 Complex
Myelin Sheath Abaxonal Region
Sarcolemma
Melanosome
Dendritic Spine
Receptor Complex
Membrane Raft
Perinuclear Region Of Cytoplasm
Recycling Endosome
Extracellular Exosome
Invadopodium Membrane
Glial Cell Projection
Schaffer Collateral - CA1 Synapse
Glutamatergic Synapse
Integral Component Of Synaptic Membrane
Stress Fiber
Ruffle
Extracellular Region
Extracellular Space
Cytoplasm
Cytosol
Actin Filament
Plasma Membrane
Brush Border
Cell-cell Junction
Fascia Adherens
Focal Adhesion
Z Disc
Platelet Alpha Granule Lumen
Pseudopodium
Cell Projection
Extracellular Exosome
Glutamatergic Synapse
Molecular Function
Virus Receptor Activity
Fibronectin Binding
Protease Binding
Actin Binding
Integrin Binding
Protein Binding
Coreceptor Activity
C-X3-C Chemokine Binding
Laminin Binding
Protein-containing Complex Binding
Cadherin Binding
Metal Ion Binding
Protein Heterodimerization Activity
Cell Adhesion Molecule Binding
Collagen Binding Involved In Cell-matrix Adhesion
Protein Tyrosine Kinase Binding
Double-stranded RNA Binding
Integrin Binding
Calcium Ion Binding
Protein Binding
Vinculin Binding
Nuclear Receptor Transcription Coactivator Activity
Protein Homodimerization Activity
Ion Channel Binding
Actin Filament Binding
Structural Constituent Of Postsynapse
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Establishment Of Mitotic Spindle Orientation
In Utero Embryonic Development
Cell Fate Specification
Cell Migration Involved In Sprouting Angiogenesis
Phagocytosis
Cellular Defense Response
Cell Adhesion
Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Leukocyte Cell-cell Adhesion
Cell-matrix Adhesion
Calcium-independent Cell-matrix Adhesion
Transforming Growth Factor Beta Receptor Signaling Pathway
Integrin-mediated Signaling Pathway
Positive Regulation Of Cell Proliferation
Germ Cell Migration
Visual Learning
Regulation Of Collagen Catabolic Process
Positive Regulation Of Fibroblast Migration
Cell Migration
Cytokine-mediated Signaling Pathway
Formation Of Radial Glial Scaffolds
CD40 Signaling Pathway
Cell Projection Organization
Lamellipodium Assembly
B Cell Differentiation
Extracellular Matrix Organization
Positive Regulation Of Cell Migration
Cell-substrate Adhesion
Receptor Internalization
Cell Adhesion Mediated By Integrin
Cell-cell Adhesion Mediated By Integrin
Heterotypic Cell-cell Adhesion
Negative Regulation Of Rho Protein Signal Transduction
Positive Regulation Of Apoptotic Process
Stress Fiber Assembly
Positive Regulation Of GTPase Activity
Sarcomere Organization
Negative Regulation Of Cell Differentiation
Positive Regulation Of Angiogenesis
Viral Entry Into Host Cell
Mesodermal Cell Differentiation
Axon Extension
Dendrite Morphogenesis
Regulation Of Immune Response
Modulation Of Chemical Synaptic Transmission
Leukocyte Migration
Leukocyte Tethering Or Rolling
Regulation Of Cell Cycle
Positive Regulation Of Protein Kinase B Signaling
Cardiac Muscle Cell Differentiation
Cellular Response To Low-density Lipoprotein Particle Stimulus
Basement Membrane Organization
Positive Regulation Of Wound Healing
Positive Regulation Of Protein Localization To Plasma Membrane
Positive Regulation Of Signaling Receptor Activity
Negative Regulation Of Anoikis
Platelet Degranulation
Actin Filament Organization
Platelet Activation
Platelet Formation
Platelet Morphogenesis
Regulation Of Apoptotic Process
Focal Adhesion Assembly
Actin Filament Bundle Assembly
Negative Regulation Of Cellular Component Movement
Actin Filament Network Formation
Actin Crosslink Formation
Platelet Aggregation
Postsynapse Organization
Positive Regulation Of Nucleic Acid-templated Transcription
Pathways
Elastic fibre formation
Fibronectin matrix formation
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Cell surface interactions at the vascular wall
Basigin interactions
Molecules associated with elastic fibres
Integrin cell surface interactions
Integrin cell surface interactions
Laminin interactions
Laminin interactions
Syndecan interactions
ECM proteoglycans
Other semaphorin interactions
Signal transduction by L1
Localization of the PINCH-ILK-PARVIN complex to focal adhesions
CHL1 interactions
RHO GTPases Activate Formins
Interleukin-4 and Interleukin-13 signaling
Platelet Adhesion to exposed collagen
MET activates PTK2 signaling
MET interacts with TNS proteins
HCMV Early Events
Platelet degranulation
Syndecan interactions
Nephrin family interactions
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Drugs
Antithymocyte immunoglobulin (rabbit)
Copper
Diseases
GWAS
Depression (quantitative trait) (
20800221
)
Suicide in bipolar disorder (
25917933
)
Cognitive decline rate in late mild cognitive impairment (
26252872
)
Feeling fed-up (
29500382
)
Feeling hurt (
29500382
)
Fibrinogen (
23969696
)
Fibrinogen levels (
28107422
)
Lack of perseverance (
30718321
)
Mean platelet volume (
27863252
)
Medication use (drugs used in diabetes) (
31015401
)
Mosquito bite size (
28199695
)
Neurociticism (
29500382
)
Periodontitis (Mean PAL) (
24024966
)
Platelet count (
26805783
29403010
)
Platelet distribution width (
27863252
)
Prostate cancer (
23535732
)
Rheumatoid arthritis (ACPA-positive) (
23143596
)
Smoking behavior (
19247474
)
Urinary albumin excretion (
30220432
)
Interacting Genes
78 interacting genes:
ACAP1
ACTN1
ACTN4
ARHGAP5
CANX
CD151
CD36
CD46
CD82
CD9
CRKL
DAG1
DOK1
EFNA4
EGFR
EPS8
FBLN1
FBXO2
FERMT1
FERMT2
FERMT3
FHL2
FLNA
FLNB
FLT4
FN1
HSPD1
HSPG2
ICAM4
IGF1R
ILK
ITGA1
ITGA10
ITGA11
ITGA2
ITGA3
ITGA4
ITGA5
ITGA6
ITGA8
ITGA9
ITGAV
ITGB1BP1
ITGB1BP2
LAMA1
LGALS1
LGALS3BP
LGALS8
MAP4K4
MET
NCKIPSD
NF2
NME1
NMRK2
PDHB
PIP5K1C
PLAUR
PRKCA
PRKCE
PTK2
PXN
RAB25
RACK1
SLC3A2
SPP1
TGFBR1
TGM2
TGOLN2
TIMP2
TLN1
TNC
TSPAN4
UPF2
VCAM1
VCAN
YWHAB
ZEB1
ZNF33A
79 interacting genes:
ACTN2
ACTN3
ADORA2A
APC
ATXN2
ATXN7
CACNA1A
CAMK2A
CBY2
CDK5
CDK5R1
CDK5R2
CLIC5
COIL
COL17A1
CSRP1
CSRP3
CTNNA1
DDIAS
EPM2AIP1
ERBIN
FBP1
FXN
GFI1B
GIPC1
GIT2
GRIA4
GRIN2A
GRM5
GTF2H1
HSPB1
ICAM5
ITGB1
KAT2B
KCTD6
KPNA2
LPP
MAGEA11
MAP2
MAP3K1
MED14
MICALL2
MTDH
MTNR1A
MTNR1B
MYOT
MYOZ1
MYOZ2
MYOZ3
NEBL
NR1H3
NUMBL
OAS1
PALLD
PDHX
PDLIM1
PDLIM5
PIAS4
PKD1
PKN1
PLD2
PSEN1
PSMA1
PTK2
PTPN1
PTPN6
PYGB
RAVER1
RPS27
SIRPA
SLC2A4
SORBS2
SRC
SSX2IP
TES
TTN
VCL
XRCC4
ZYX
Entrez ID
3688
87
HPRD ID
00628
00020
Ensembl ID
ENSG00000150093
ENSG00000072110
Uniprot IDs
P05556
A0A024R694
P12814
PDB IDs
1K11
1LHA
3G9W
3T9K
3VI3
3VI4
4DX9
4WJK
4WK0
4WK2
4WK4
2EYI
2EYN
2N8Y
2N8Z
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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