EPS8 and MYO15A

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EPS8	MYO15A
Description		epidermal growth factor receptor pathway substrate 8	myosin XVA
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Brush Border Cell Cortex Postsynaptic Density NMDA Selective Glutamate Receptor Complex Cell Junction Growth Cone Vesicle Stereocilium Stereocilium Tip Ruffle Membrane Extracellular Exosome Glutamatergic Synapse	Cytoplasm Actin Cytoskeleton Myosin Complex Vesicle Stereocilium Extracellular Exosome Actin-based Cell Projection
	Molecular Function	Actin Binding Protein Binding Rac Guanyl-nucleotide Exchange Factor Activity Signaling Adaptor Activity Rac GTPase Binding	Microfilament Motor Activity Motor Activity Actin Binding Calmodulin Binding ATP Binding Actin-dependent ATPase Activity Actin Filament Binding
	Biological Process	Rho Protein Signal Transduction Adult Locomotory Behavior Regulation Of Cell Shape Positive Regulation Of Signal Transduction Exit From Mitosis Rac Protein Signal Transduction Regulation Of Actin Filament Length Actin Cytoskeleton Reorganization Regulation Of Rho Protein Signal Transduction Dendritic Cell Migration Behavioral Response To Ethanol Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Actin Crosslink Formation Actin Polymerization-dependent Cell Motility Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Positive Regulation Of Ruffle Assembly Cellular Response To Leukemia Inhibitory Factor	Actin Filament Organization Sensory Perception Of Sound Locomotory Behavior Vesicle Transport Along Actin Filament Inner Ear Morphogenesis
Pathways
Drugs
Diseases			Deafness, autosomal recessive
GWAS		Metabolite levels ( 23823483) Protein quantitative trait loci ( 18464913)	Change in neurofilament light levels ( 31295725) Obesity-related traits ( 23251661) Schizophrenia ( 25056061) Serum folate levels ( 29953918)
Interacting Genes		61 interacting genes: ABI1 ACTA1 ADAM22 AIMP2 ALDH7A1 ARMC1 BAIAP2 BCKDK BLOC1S6 BORCS6 BYSL C19orf25 C6orf141 C8orf33 CASK CBL CCDC85B CSNK2B CTNNA3 CXCL2 DNALI1 DVL1 EGFR GOLGA8EP GRB2 GULP1 HNRNPC HOOK2 INPP5J ITGB1 ITGB3 ITGB5 ITSN2 MAP1LC3B MAP3K11 MRPL20 MYO15A NACC2 NFKB2 PCM1 PROSER2 RCAN3 RFXAP RSPH14 RUNX1T1 SCRN3 SERPINA5 SF3B3 SHB SHC1 SLC27A4 SMARCE1 SOS1 SRC TDP2 TEX28 TPRN USP6NL XAGE2 XRCC6 ZZZ3	4 interacting genes: EPS8 FASLG USP13 WHRN
Entrez ID		2059	51168
HPRD ID		02563	04049
Ensembl ID		ENSG00000151491	ENSG00000091536
Uniprot IDs		B4E3T6 Q12929	Q9UKN7
PDB IDs		2E8M
Enriched GO Terms of Interacting Partners?
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