UBE2S and STAMBP

Number of citations of the paper that reports this interaction (PubMedID 20622874)
119

Data Source:
BioGRID (enzymatic study)

		UBE2S	STAMBP
Description		ubiquitin conjugating enzyme E2 S	STAM binding protein
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GO Annotations	Cellular Component	Cell Nucleoplasm Anaphase-promoting Complex Cytosol	Nucleus Nucleoplasm Endosome Early Endosome Cytosol Plasma Membrane Membrane Cleavage Furrow Extracellular Exosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Anaphase-promoting Complex Binding Ubiquitin Conjugating Enzyme Activity	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Metallopeptidase Activity Protein Domain Specific Binding Metal Ion Binding Lys63-specific Deubiquitinase Activity
	Biological Process	Protein Polyubiquitination Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Exit From Mitosis Free Ubiquitin Chain Polymerization Protein Ubiquitination Anaphase-promoting Complex-dependent Catabolic Process Protein K29-linked Ubiquitination Protein K27-linked Ubiquitination Cell Division Protein K63-linked Ubiquitination Protein K11-linked Ubiquitination Protein K6-linked Ubiquitination Positive Regulation Of Ubiquitin Protein Ligase Activity	Mitotic Cytokinesis JAK-STAT Cascade Positive Regulation Of Cell Proliferation Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Protein Deubiquitination Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Ras Protein Signal Transduction Protein K63-linked Deubiquitination
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation	Metalloprotease DUBs
Drugs
Diseases
GWAS			Anti-saccade response ( 29064472) Blood metabolite levels ( 26401656) Serum metabolite levels ( 23093944)
Interacting Genes		40 interacting genes: AKT1 ANAPC1 ANAPC11 ANAPC2 ANAPC4 ANAPC5 ANAPC7 APP ATXN3 BIRC2 CDC16 CDC20 CDC23 CDC27 CTNNB1 CYLD FBXO5 FZR1 GMNN HERC1 LINC00839 MDM2 OTUB1 OTUD7B PRKN PTEN RBCK1 RNF7 STAMBP UBA1 UBA6 UBB UBC UCHL3 USP15 USP2 USP21 USP5 USP7 ZRANB1	43 interacting genes: ALAS1 AMN BMPR1B CASR CHMP1A CHMP1B CHMP2A CHMP3 CHMP4A CHMP4B CHMP4C CHMP5 CLTC CTNNBL1 CYP2C9 EPS15 GRAP2 GRB2 IL1RL2 ITGA5 MAP2K5 MAP3K2 NLRP7 NTPCR PJA1 RECQL5 RNF11 SMAD2 SMAD6 SMAD7 SNCA SPG7 STAM STAM2 TNFRSF1A TP53 TRAF6 TRIP13 UACA UBC UBE2S USP21 USP28
Entrez ID		27338	10617
HPRD ID		15603	05877
Ensembl ID		ENSG00000108106	ENSG00000124356
Uniprot IDs		Q16763	A0A140VK54 O95630
PDB IDs		1ZDN 5BNB 5L9T 6QH3 6QHK	2XZE 3RZU 3RZV 5IXF
Enriched GO Terms of Interacting Partners?
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