UBE2S and USP5

Number of citations of the paper that reports this interaction (PubMedID 20622874)
119

Data Source:
BioGRID (enzymatic study)

		UBE2S	USP5
Description		ubiquitin conjugating enzyme E2 S	ubiquitin specific peptidase 5
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GO Annotations	Cellular Component	Cell Nucleoplasm Anaphase-promoting Complex Cytosol	Lysosome Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Anaphase-promoting Complex Binding Ubiquitin Conjugating Enzyme Activity	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding Thiol-dependent Ubiquitinyl Hydrolase Activity Ubiquitin Binding
	Biological Process	Protein Polyubiquitination Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Exit From Mitosis Free Ubiquitin Chain Polymerization Protein Ubiquitination Anaphase-promoting Complex-dependent Catabolic Process Protein K29-linked Ubiquitination Protein K27-linked Ubiquitination Cell Division Protein K63-linked Ubiquitination Protein K11-linked Ubiquitination Protein K6-linked Ubiquitination Positive Regulation Of Ubiquitin Protein Ligase Activity	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Deubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Deubiquitination
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation	Ub-specific processing proteases Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Drugs
Diseases
GWAS
Interacting Genes		40 interacting genes: AKT1 ANAPC1 ANAPC11 ANAPC2 ANAPC4 ANAPC5 ANAPC7 APP ATXN3 BIRC2 CDC16 CDC20 CDC23 CDC27 CTNNB1 CYLD FBXO5 FZR1 GMNN HERC1 LINC00839 MDM2 OTUB1 OTUD7B PRKN PTEN RBCK1 RNF7 STAMBP UBA1 UBA6 UBB UBC UCHL3 USP15 USP2 USP21 USP5 USP7 ZRANB1	23 interacting genes: APP CACNA1H DAZAP2 DVL2 PJA1 PLA2G2A RFFL RNF11 SMURF1 STK33 TADA3 TMEM239 TRAF6 TRIM26 TRIM39 TRIM5 TRIM54 TRIM55 TRIM63 TRIML1 UBE2S UBTD2 USP28
Entrez ID		27338	8078
HPRD ID		15603	03265
Ensembl ID		ENSG00000108106	ENSG00000111667
Uniprot IDs		Q16763	A0A140VJZ1 P45974
PDB IDs		1ZDN 5BNB 5L9T 6QH3 6QHK	2DAG 2DAK 2G43 2G45 3IHP 6DXH 6DXT 6NFT 6P9G
Enriched GO Terms of Interacting Partners?
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