UBE2S and ZRANB1

Number of citations of the paper that reports this interaction (PubMedID 20622874)
119

Data Source:
BioGRID (enzymatic study)

		UBE2S	ZRANB1
Description		ubiquitin conjugating enzyme E2 S	zinc finger RANBP2-type containing 1
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GO Annotations	Cellular Component	Cell Nucleoplasm Anaphase-promoting Complex Cytosol	Nucleus Nucleoplasm Cytoplasm Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Anaphase-promoting Complex Binding Ubiquitin Conjugating Enzyme Activity	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Thiol-dependent Ubiquitinyl Hydrolase Activity Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Protein Polyubiquitination Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Exit From Mitosis Free Ubiquitin Chain Polymerization Protein Ubiquitination Anaphase-promoting Complex-dependent Catabolic Process Protein K29-linked Ubiquitination Protein K27-linked Ubiquitination Cell Division Protein K63-linked Ubiquitination Protein K11-linked Ubiquitination Protein K6-linked Ubiquitination Positive Regulation Of Ubiquitin Protein Ligase Activity	Cytoskeleton Organization Wnt Signaling Pathway Cell Migration Protein Deubiquitination Regulation Of Cell Morphogenesis Positive Regulation Of Wnt Signaling Pathway Protein K29-linked Deubiquitination Protein K63-linked Deubiquitination Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein K33-linked Deubiquitination
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation	Degradation of beta-catenin by the destruction complex Ovarian tumor domain proteases
Drugs
Diseases
GWAS			Blood urea nitrogen levels ( 31152163) Creatine kinase levels ( 29403010) Height ( 25429064 31562340)
Interacting Genes		40 interacting genes: AKT1 ANAPC1 ANAPC11 ANAPC2 ANAPC4 ANAPC5 ANAPC7 APP ATXN3 BIRC2 CDC16 CDC20 CDC23 CDC27 CTNNB1 CYLD FBXO5 FZR1 GMNN HERC1 LINC00839 MDM2 OTUB1 OTUD7B PRKN PTEN RBCK1 RNF7 STAMBP UBA1 UBA6 UBB UBC UCHL3 USP15 USP2 USP21 USP5 USP7 ZRANB1	9 interacting genes: AKT1 CORO7 CSNK1A1 SNCA TRAF6 TWIST1 UBC UBE2S UVRAG
Entrez ID		27338	54764
HPRD ID		15603	11738
Ensembl ID		ENSG00000108106	ENSG00000019995
Uniprot IDs		Q16763	Q9UGI0
PDB IDs		1ZDN 5BNB 5L9T 6QH3 6QHK	3ZRH 5AF6
Enriched GO Terms of Interacting Partners?
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