ZNF688 and HMBOX1

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		ZNF688	HMBOX1
Description		zinc finger protein 688	homeobox containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus	Nuclear Chromosome, Telomeric Region Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cajal Body Nuclear Body PML Body
	Molecular Function	Molecular_function DNA-binding Transcription Factor Activity Sequence-specific DNA Binding Metal Ion Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Double-stranded Telomeric DNA Binding Protein Binding Telomeric DNA Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding
	Biological Process	Regulation Of Transcription, DNA-templated Biological_process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Chromatin Binding Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Telomerase Activity Positive Regulation Of Telomerase Activity
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Interacting Genes		70 interacting genes: ABI2 BEND5 BLZF1 CADPS CALCOCO2 CARD9 CBY2 CCDC136 CCDC33 CCDC57 CEP44 CEP70 CEP72 CRX EHMT2 FBXO7 FCHO1 FHL5 GMPPA GOLGA2 GPRASP2 HMBOX1 HNRNPK HOMEZ IHO1 KHDRBS2 KHDRBS3 KIFC3 KRT13 KRT15 KRT31 KRT40 KRTAP10-3 KRTAP10-9 KRTAP12-2 KRTAP4-2 LDOC1 MAGED1 MDFI MEOX2 MID2 MIPOL1 MKRN3 NOTCH2NLA PCBD1 PLSCR1 PNMA1 PNMA2 PSMA3 PSTPIP1 REL RFX6 RINT1 RPGRIP1 SPAG5 SSX2IP TADA2A TCF12 TCF4 TMCC2 TNS2 TRAF1 TRAF2 TRAF4 TRIM23 TRIM27 TRIP6 USHBP1 WWP2 ZC4H2	49 interacting genes: ABITRAM AEBP2 APP ATP5PO BYSL C8orf33 CARD9 CBX8 CCNG1 DAB1 DYNLL2 ENTPD2 FAM13C FAM161A FAM74A4 FARS2 FNDC11 FRMD6 FXR2 KAT5 LNX1 MAGEH1 MFAP1 MORF4L1 MRPL11 MRPL28 PIP4K2B PKD1P1 PRKAA1 PRKAA2 RBMY2FP REEP6 RPL9 SAP30L SFR1 SH2D4A SNRPB2 TCEANC UBA6 UBE2Z VPS72 WT1 ZBTB24 ZMAT2 ZNF337 ZNF417 ZNF581 ZNF587 ZNF688
Entrez ID		146542	79618
HPRD ID		14070	07964
Ensembl ID		ENSG00000229809	ENSG00000147421
Uniprot IDs		A0A024QZB6 A0A0S2Z633 P0C7X2	D3DSU2 Q6NT76
PDB IDs			2CUF 4J19
Enriched GO Terms of Interacting Partners?
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