HMBOX1 and MFAP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HMBOX1	MFAP1
Description		homeobox containing 1	microfibril associated protein 1
Image
GO Annotations	Cellular Component	Nuclear Chromosome, Telomeric Region Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cajal Body Nuclear Body PML Body	Microfibril Extracellular Region Nucleus Nucleoplasm Centrosome U2-type Precatalytic Spliceosome
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Double-stranded Telomeric DNA Binding Protein Binding Telomeric DNA Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding	RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Chromatin Binding Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Telomerase Activity Positive Regulation Of Telomerase Activity	MRNA Splicing, Via Spliceosome
Pathways			Molecules associated with elastic fibres
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Lipoprotein phospholipase A2 activity in cardiovascular disease ( 28753643)
Interacting Genes		49 interacting genes: ABITRAM AEBP2 APP ATP5PO BYSL C8orf33 CARD9 CBX8 CCNG1 DAB1 DYNLL2 ENTPD2 FAM13C FAM161A FAM74A4 FARS2 FNDC11 FRMD6 FXR2 KAT5 LNX1 MAGEH1 MFAP1 MORF4L1 MRPL11 MRPL28 PIP4K2B PKD1P1 PRKAA1 PRKAA2 RBMY2FP REEP6 RPL9 SAP30L SFR1 SH2D4A SNRPB2 TCEANC UBA6 UBE2Z VPS72 WT1 ZBTB24 ZMAT2 ZNF337 ZNF417 ZNF581 ZNF587 ZNF688	47 interacting genes: AMOTL2 BEND7 CARD9 CCDC57 CDCA7L CEP55 CEP57L1 CEP70 COIL CSNK2A1 DHX38 DHX8 FAM9B FRA10AC1 FXR2 GKAP1 GOLGA2 HMBOX1 HSPB1 IK KATNBL1 KIFC3 KRT40 LDOC1 LMNA MAD1L1 MID2 MIPOL1 MTUS2 NDC80 PHC2 SART1 SNIP1 SNW1 SSX2IP STX11 TADA2A TLE5 TRIM42 TRIM54 U2AF1 VPS52 YWHAG ZBTB14 ZBTB8A ZFP64 ZNF398
Entrez ID		79618	4236
HPRD ID		07964	02569
Ensembl ID		ENSG00000147421	ENSG00000140259
Uniprot IDs		D3DSU2 Q6NT76	P55081
PDB IDs		2CUF 4J19	5F5S 5O9Z 6AHD
Enriched GO Terms of Interacting Partners?
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