HMBOX1 and ZMAT2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HMBOX1	ZMAT2
Description		homeobox containing 1	zinc finger matrin-type 2
Image
GO Annotations	Cellular Component	Nuclear Chromosome, Telomeric Region Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cajal Body Nuclear Body PML Body	Nucleus U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Double-stranded Telomeric DNA Binding Protein Binding Telomeric DNA Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Chromatin Binding Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Telomerase Activity Positive Regulation Of Telomerase Activity	MRNA Splicing, Via Spliceosome
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Major depressive disorder ( 27479909) Schizophrenia ( 28991256 29483656) Systolic blood pressure ( 30224653)
Interacting Genes		49 interacting genes: ABITRAM AEBP2 APP ATP5PO BYSL C8orf33 CARD9 CBX8 CCNG1 DAB1 DYNLL2 ENTPD2 FAM13C FAM161A FAM74A4 FARS2 FNDC11 FRMD6 FXR2 KAT5 LNX1 MAGEH1 MFAP1 MORF4L1 MRPL11 MRPL28 PIP4K2B PKD1P1 PRKAA1 PRKAA2 RBMY2FP REEP6 RPL9 SAP30L SFR1 SH2D4A SNRPB2 TCEANC UBA6 UBE2Z VPS72 WT1 ZBTB24 ZMAT2 ZNF337 ZNF417 ZNF581 ZNF587 ZNF688	25 interacting genes: AK8 AMH CBY2 CCDC57 CEP76 FSD2 FXR2 GOLGA2 HMBOX1 IKZF1 KRT40 LZTS2 MEOX2 MTUS2 PHC2 SPAG5 SSX2IP TFEC TFIP11 TRAF2 TRIM36 TRIM37 VPS52 ZBTB14 ZBTB8A
Entrez ID		79618	153527
HPRD ID		07964	08094
Ensembl ID		ENSG00000147421	ENSG00000146007
Uniprot IDs		D3DSU2 Q6NT76	Q96NC0
PDB IDs		2CUF 4J19	5O9Z 6AHD
Enriched GO Terms of Interacting Partners?
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