HMBOX1 and MRPL11

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HMBOX1	MRPL11
Description		homeobox containing 1	mitochondrial ribosomal protein L11
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GO Annotations	Cellular Component	Nuclear Chromosome, Telomeric Region Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cajal Body Nuclear Body PML Body	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome Mitochondrial Large Ribosomal Subunit Ribosome Large Ribosomal Subunit
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Double-stranded Telomeric DNA Binding Protein Binding Telomeric DNA Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding Large Ribosomal Subunit RRNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Chromatin Binding Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Telomerase Activity Positive Regulation Of Telomerase Activity	Ribosomal Large Subunit Assembly Translation Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways			Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Bipolar disorder ( 21926972)
Interacting Genes		49 interacting genes: ABITRAM AEBP2 APP ATP5PO BYSL C8orf33 CARD9 CBX8 CCNG1 DAB1 DYNLL2 ENTPD2 FAM13C FAM161A FAM74A4 FARS2 FNDC11 FRMD6 FXR2 KAT5 LNX1 MAGEH1 MFAP1 MORF4L1 MRPL11 MRPL28 PIP4K2B PKD1P1 PRKAA1 PRKAA2 RBMY2FP REEP6 RPL9 SAP30L SFR1 SH2D4A SNRPB2 TCEANC UBA6 UBE2Z VPS72 WT1 ZBTB24 ZMAT2 ZNF337 ZNF417 ZNF581 ZNF587 ZNF688	16 interacting genes: APP CAMK2B CAMK2D CRYAB FSD2 HMBOX1 HOMEZ JAKMIP2 KRT40 MTUS2 PNMA1 SLC16A9 TAX1BP1 TFCP2 THAP1 VPS52
Entrez ID		79618	65003
HPRD ID		07964	14739
Ensembl ID		ENSG00000147421	ENSG00000174547
Uniprot IDs		D3DSU2 Q6NT76	Q9Y3B7
PDB IDs		2CUF 4J19	3J7Y 3J9M 5OOL 5OOM 6NU2 6NU3
Enriched GO Terms of Interacting Partners?
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