HMBOX1 and ZNF417

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HMBOX1	ZNF417
Description		homeobox containing 1	zinc finger protein 417
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome, Telomeric Region Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cajal Body Nuclear Body PML Body	Nucleus
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Double-stranded Telomeric DNA Binding Protein Binding Telomeric DNA Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Chromatin Binding Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Telomerase Activity Positive Regulation Of Telomerase Activity	Regulation Of Transcription, DNA-templated
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Depression in smokers ( 30219690)
Interacting Genes		49 interacting genes: ABITRAM AEBP2 APP ATP5PO BYSL C8orf33 CARD9 CBX8 CCNG1 DAB1 DYNLL2 ENTPD2 FAM13C FAM161A FAM74A4 FARS2 FNDC11 FRMD6 FXR2 KAT5 LNX1 MAGEH1 MFAP1 MORF4L1 MRPL11 MRPL28 PIP4K2B PKD1P1 PRKAA1 PRKAA2 RBMY2FP REEP6 RPL9 SAP30L SFR1 SH2D4A SNRPB2 TCEANC UBA6 UBE2Z VPS72 WT1 ZBTB24 ZMAT2 ZNF337 ZNF417 ZNF581 ZNF587 ZNF688	68 interacting genes: ADAMTSL4 BEGAIN BEND5 CARD9 CCDC136 CCDC57 CCDC85B CCNDBP1 CEP44 CEP70 CEP72 CSRNP1 EFS FHL2 FHL3 FSD2 GOLGA2 HMBOX1 IKZF1 KLC3 KRT15 KRT38 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 KRTAP5-9 KXD1 LURAP1 LZTS2 MDFI MEOX2 MID2 MTUS2 NDEL1 NINL NOTCH2NLA PHC2 PLSCR1 PNMA2 PRPF31 REL RPGRIP1 RUNDC3A SPRY2 SSX2IP STX11 TCF4 TFIP11 TMCC2 TNS2 TRAF1 TRIM27 TRIM36 TRIM37 TRIM41 TRIM54 TSGA10 ZBTB1 ZBTB10 ZBTB43 ZBTB8A ZNF587
Entrez ID		79618	147687
HPRD ID		07964	18341
Ensembl ID		ENSG00000147421	ENSG00000173480
Uniprot IDs		D3DSU2 Q6NT76	M0R230 Q8TAU3
PDB IDs		2CUF 4J19
Enriched GO Terms of Interacting Partners?
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