ZNF688 and CRX

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		ZNF688	CRX
Description		zinc finger protein 688	cone-rod homeobox
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus	Nuclear Chromatin Nucleus
	Molecular Function	Molecular_function DNA-binding Transcription Factor Activity Sequence-specific DNA Binding Metal Ion Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Nuclear Hormone Receptor Binding Leucine Zipper Domain Binding
	Biological Process	Regulation Of Transcription, DNA-templated Biological_process	Regulation Of Transcription, DNA-templated Nervous System Development Visual Perception Animal Organ Morphogenesis Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Response To Stimulus
Pathways		Generic Transcription Pathway
Drugs
Diseases			Leber congenital amaurosis (LCR) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS
Interacting Genes		70 interacting genes: ABI2 BEND5 BLZF1 CADPS CALCOCO2 CARD9 CBY2 CCDC136 CCDC33 CCDC57 CEP44 CEP70 CEP72 CRX EHMT2 FBXO7 FCHO1 FHL5 GMPPA GOLGA2 GPRASP2 HMBOX1 HNRNPK HOMEZ IHO1 KHDRBS2 KHDRBS3 KIFC3 KRT13 KRT15 KRT31 KRT40 KRTAP10-3 KRTAP10-9 KRTAP12-2 KRTAP4-2 LDOC1 MAGED1 MDFI MEOX2 MID2 MIPOL1 MKRN3 NOTCH2NLA PCBD1 PLSCR1 PNMA1 PNMA2 PSMA3 PSTPIP1 REL RFX6 RINT1 RPGRIP1 SPAG5 SSX2IP TADA2A TCF12 TCF4 TMCC2 TNS2 TRAF1 TRAF2 TRAF4 TRIM23 TRIM27 TRIP6 USHBP1 WWP2 ZC4H2	54 interacting genes: ABI2 ACBD4 ATG12 ATM ATXN7 BANF1 BANP C1orf109 C9orf72 CA8 CCNC CREBBP CSNK1G2-AS1 DELE1 EIF5A EP300 GCM2 GUCD1 HGS IPO13 KAT2A KLHL32 LARP4 LONRF1 M1AP MDFI MLLT6 NIP7 NPAS2 NR2E3 NRL OSGIN1 PDC PICALM PID1 PPP1R16B PRKAB2 PRKN PSMB10 PSMF1 QRICH1 RAX2 RBFOX1 RBPMS ROR2 SFI1 SMAD3 SMUG1 SOX5 STK16 SZT2 TLE5 UBXN2B ZNF688
Entrez ID		146542	1406
HPRD ID		14070	03748
Ensembl ID		ENSG00000229809	ENSG00000105392
Uniprot IDs		A0A024QZB6 A0A0S2Z633 P0C7X2	O43186
PDB IDs
Enriched GO Terms of Interacting Partners?
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