ATG13 and ATG14

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		ATG13	ATG14
Description		autophagy related 13	autophagy related 14
Image
GO Annotations	Cellular Component	Phagophore Assembly Site Mitochondrion Endoplasmic Reticulum Membrane Cytosol Extrinsic Component Of Membrane Atg1/ULK1 Kinase Complex	Autophagosome Membrane Autophagosome Endoplasmic Reticulum Membrane Cytosol Axoneme Phagophore Assembly Site Membrane Phosphatidylinositol 3-kinase Complex, Class III Mitochondria-associated Endoplasmic Reticulum Membrane Phagocytic Vesicle Extrinsic Component Of Omegasome Membrane Extrinsic Component Of Phagophore Assembly Site Membrane
	Molecular Function	Protein Binding Protein Kinase Binding	Protein Binding GTPase Binding
	Biological Process	Autophagosome Assembly Mitophagy Macroautophagy Regulation Of Macroautophagy Protein Localization To Phagophore Assembly Site Piecemeal Microautophagy Of The Nucleus Response To Mitochondrial Depolarisation Positive Regulation Of Protein Targeting To Mitochondrion	Autophagosome Assembly Mitophagy Regulation Of Protein Phosphorylation Negative Regulation Of Protein Phosphorylation Positive Regulation Of Protein Phosphorylation Endosome To Lysosome Transport Cellular Response To Starvation Posttranscriptional Regulation Of Gene Expression Macroautophagy Autophagosome Membrane Docking Cellular Response To Glucose Starvation Positive Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of Protein Complex Stability Regulation Of Triglyceride Metabolic Process Response To Mitochondrial Depolarisation
Pathways		Macroautophagy	Macroautophagy
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 27089180) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Headache ( 29397368) Immunoglobulin A ( 20694011) Reaction time ( 29844566) Schizophrenia ( 29483656) Selective IgA deficiency ( 27723758)	Blood protein levels ( 28240269) Eosinophil percentage of white cells ( 32888494) Platelet distribution width ( 27863252) Statin-induced myopathy ( 31220337) Testicular germ cell tumor ( 28604728) White blood cell count ( 32888494)
Interacting Genes		10 interacting genes: APP ATG101 ATG14 GABARAP GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B MAP1LC3C SMCR8	9 interacting genes: ATG13 EXOC1 FSD2 MIS18A RACK1 SNAPIN STX17 STYK1 ULK2
Entrez ID		9776	22863
HPRD ID		13809	13820
Ensembl ID		ENSG00000175224	ENSG00000126775
Uniprot IDs		A8K0S6 O75143	Q6ZNE5
PDB IDs		3WAN 3WAO 3WAP 5C50 5XUY 5XV1 5XV3 5XV4 5XV6 6HYN	6HOL
Enriched GO Terms of Interacting Partners?
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