ATG13 and MAP1LC3B

Data Source:
BioGRID (affinity chromatography technology, pull down, x-ray crystallography)

		ATG13	MAP1LC3B
Description		autophagy related 13	microtubule associated protein 1 light chain 3 beta
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GO Annotations	Cellular Component	Phagophore Assembly Site Mitochondrion Endoplasmic Reticulum Membrane Cytosol Extrinsic Component Of Membrane Atg1/ULK1 Kinase Complex	Autophagosome Membrane Mitochondrion Autophagosome Cytosol Microtubule Axoneme Endomembrane System Organelle Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Protein Kinase Binding	Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding
	Biological Process	Autophagosome Assembly Mitophagy Macroautophagy Regulation Of Macroautophagy Protein Localization To Phagophore Assembly Site Piecemeal Microautophagy Of The Nucleus Response To Mitochondrial Depolarisation Positive Regulation Of Protein Targeting To Mitochondrion	Autophagosome Assembly Autophagy Of Mitochondrion Mitophagy Autophagy Cellular Response To Nitrogen Starvation Cellular Response To Starvation Macroautophagy Autophagosome Maturation
Pathways		Macroautophagy	Macroautophagy PINK1-PRKN Mediated Mitophagy TBC/RABGAPs Receptor Mediated Mitophagy Pexophagy Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 27089180) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Headache ( 29397368) Immunoglobulin A ( 20694011) Reaction time ( 29844566) Schizophrenia ( 29483656) Selective IgA deficiency ( 27723758)	General factor of neuroticism ( 30867560) Major depressive disorder ( 22472876) Metabolite levels ( 23823483) Neuroticism ( 29255261) Refractive error ( 32231278)
Interacting Genes		10 interacting genes: APP ATG101 ATG14 GABARAP GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B MAP1LC3C SMCR8	66 interacting genes: AAMP ADD1 ADNP AMBRA1 ANK2 ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4C ATG4D ATG7 BIRC6 BNIP3 BRD3 CASP8 CCSER2 CLTA CUL3 DBI DBN1 DNMT3B EED EPS8 EVA1A FLCN FUNDC1 GABARAPL2 GORASP2 IRGQ KBTBD7 KLHL5 KXD1 LUC7L2 MESD MKRN1 MRFAP1 MYBL2 NBR1 NEDD4 RAD1 RAP1GAP RETREG2 RIPOR1 RPLP1 SEM1 SMARCB1 SNU13 SNX18 SPAG9 SQSTM1 TAF7 TAX1BP1 TBC1D17 TBC1D25 TBC1D9 TBC1D9B TBK1 THAP7 TMOD3 TNIP1 TRIM21 TRIM32 UPF2 VHL
Entrez ID		9776	81631
HPRD ID		13809	14358
Ensembl ID		ENSG00000175224	ENSG00000140941
Uniprot IDs		A8K0S6 O75143	Q658J6 Q9GZQ8
PDB IDs		3WAN 3WAO 3WAP 5C50 5XUY 5XV1 5XV3 5XV4 5XV6 6HYN	1V49 2LUE 2N9X 2ZJD 3VTU 3VTV 3VTW 3WAO 3X0W 4WAA 5D94 5DCN 5GMV 5MS2 5MS5 5MS6 5V4K 5W9A 5XAC 5XAD 5XAE 6J04 6LAN
Enriched GO Terms of Interacting Partners?
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