ATG14 and MIS18A

Data Source:
BioGRID (two hybrid)

		ATG14	MIS18A
Description		autophagy related 14	MIS18 kinetochore protein A
Image			No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Autophagosome Endoplasmic Reticulum Membrane Cytosol Axoneme Phagophore Assembly Site Membrane Phosphatidylinositol 3-kinase Complex, Class III Mitochondria-associated Endoplasmic Reticulum Membrane Phagocytic Vesicle Extrinsic Component Of Omegasome Membrane Extrinsic Component Of Phagophore Assembly Site Membrane	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding GTPase Binding	Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Autophagosome Assembly Mitophagy Regulation Of Protein Phosphorylation Negative Regulation Of Protein Phosphorylation Positive Regulation Of Protein Phosphorylation Endosome To Lysosome Transport Cellular Response To Starvation Posttranscriptional Regulation Of Gene Expression Macroautophagy Autophagosome Membrane Docking Cellular Response To Glucose Starvation Positive Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of Protein Complex Stability Regulation Of Triglyceride Metabolic Process Response To Mitochondrial Depolarisation	Cell Cycle Chromosome Segregation CENP-A Containing Nucleosome Assembly Regulation Of DNA Methylation Cell Division
Pathways		Macroautophagy	Deposition of new CENPA-containing nucleosomes at the centromere
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Eosinophil percentage of white cells ( 32888494) Platelet distribution width ( 27863252) Statin-induced myopathy ( 31220337) Testicular germ cell tumor ( 28604728) White blood cell count ( 32888494)
Interacting Genes		9 interacting genes: ATG13 EXOC1 FSD2 MIS18A RACK1 SNAPIN STX17 STYK1 ULK2	30 interacting genes: ABI3 AIMP2 AMOT ATG14 BRD8 C1orf216 CCDC115 CNGA3 DMAP1 FNDC11 GCSH GLYCTK HJURP IFT20 MAFIP MBIP NDEL1 NTAQ1 NUP58 OIP5 PPP1R13B RTP5 STX11 STX17 TEDC2 THAP1 TSGA10IP TXLNA ZNF471 ZNF655
Entrez ID		22863	54069
HPRD ID		13820	10749
Ensembl ID		ENSG00000126775	ENSG00000159055
Uniprot IDs		Q6ZNE5	Q9NYP9
PDB IDs		6HOL
Enriched GO Terms of Interacting Partners?
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