ATG14 and FSD2

Data Source:
BioGRID (two hybrid)

		ATG14	FSD2
Description		autophagy related 14	fibronectin type III and SPRY domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Autophagosome Endoplasmic Reticulum Membrane Cytosol Axoneme Phagophore Assembly Site Membrane Phosphatidylinositol 3-kinase Complex, Class III Mitochondria-associated Endoplasmic Reticulum Membrane Phagocytic Vesicle Extrinsic Component Of Omegasome Membrane Extrinsic Component Of Phagophore Assembly Site Membrane	Nucleus Sarcoplasmic Reticulum Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding GTPase Binding	Protein Binding
	Biological Process	Autophagosome Assembly Mitophagy Regulation Of Protein Phosphorylation Negative Regulation Of Protein Phosphorylation Positive Regulation Of Protein Phosphorylation Endosome To Lysosome Transport Cellular Response To Starvation Posttranscriptional Regulation Of Gene Expression Macroautophagy Autophagosome Membrane Docking Cellular Response To Glucose Starvation Positive Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of Protein Complex Stability Regulation Of Triglyceride Metabolic Process Response To Mitochondrial Depolarisation
Pathways		Macroautophagy
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Eosinophil percentage of white cells ( 32888494) Platelet distribution width ( 27863252) Statin-induced myopathy ( 31220337) Testicular germ cell tumor ( 28604728) White blood cell count ( 32888494)	HDL cholesterol levels ( 32203549) Tourette syndrome ( 30818990)
Interacting Genes		9 interacting genes: ATG13 EXOC1 FSD2 MIS18A RACK1 SNAPIN STX17 STYK1 ULK2	94 interacting genes: AQP1 ARFIP2 ATF7IP2 ATG14 ATXN7L2 BEX2 BEX3 BRD8 C1orf216 CAMSAP3 CBX8 CCDC112 CCDC120 CCDC146 CCDC187 CCHCR1 CDC73 CDK18 CORO1A CTAG1A CTAG1B CWF19L2 DCX DTNB ENKD1 ESD EXOC3 FAM107A FAM110A FAM161A FAM50B FAM90A1 FARS2 FMR1 HDAC4 HGS IFT20 KANSL1 KLHL40 LATS1 LENG1 LNX1 MCRS1 MID2 MRPL11 MYBPC2 NDN OIP5 OXNAD1 PBX3 PIK3R3 PNMA5 POLL PPP1R18 PPP2R5D PRPF18 PRPF31 PSMB4 RCOR3 RNF8 SCNM1 SH2D4A SMARCE1 SNAPIN SPATC1L TCEANC THAP7 TLE5 TSGA10IP TTC23 UBTFL1 VEZF1 ZBTB38 ZC2HC1C ZMAT2 ZNF124 ZNF20 ZNF230 ZNF35 ZNF408 ZNF410 ZNF417 ZNF490 ZNF572 ZNF580 ZNF581 ZNF587 ZNF648 ZNF76 ZNF774 ZNF777 ZNF835 ZNF837 ZSCAN26
Entrez ID		22863	123722
HPRD ID		13820	17291
Ensembl ID		ENSG00000126775	ENSG00000186628
Uniprot IDs		Q6ZNE5	A1L4K1 B7ZM05
PDB IDs		6HOL
Enriched GO Terms of Interacting Partners?
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