CD151 and RNF128

Data Source:
HPRD (in vivo)

		CD151	RNF128
Description		CD151 molecule (Raph blood group)	ring finger protein 128
Image		No pdb structure
GO Annotations	Cellular Component	Basement Membrane Cytosol Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Cell Surface Membrane	Cytoplasm Late Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Cytoskeleton Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Integrin Binding Protein Binding	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Cell Adhesion Viral Process Cell Migration Positive Regulation Of Cell Migration Hemidesmosome Assembly T Cell Proliferation Wound Healing, Spreading Of Cells Positive Regulation Of Endocytosis	Negative Regulation Of Cytokine Production Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Deubiquitination Regulation Of Protein Stability Protein Localization To Lysosome Positive Regulation Of Protein Catabolic Process In The Vacuole
Pathways		Assembly of collagen fibrils and other multimeric structures Type I hemidesmosome assembly	Ub-specific processing proteases Ovarian tumor domain proteases
Drugs
Diseases		Nephropathy with pretibial epidermolysis bullosa and deafness
GWAS		Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494)	Alcoholic chronic pancreatitis ( 28754779) Creatinine levels ( 31015462) Estimated glomerular filtration rate ( 31015462)
Interacting Genes		12 interacting genes: ARL13B BCL7A GRAMD1C ITGA3 ITGA6 ITGB1 KLRC1 MMP7 PTGFRN RNF128 TMEM139 TSPAN18	16 interacting genes: APPBP2 CD151 CD40LG CD81 CEP76 OTUB1 SNX17 TBK1 TP53 UBE2D1 UBE2E1 UBE2H UBE2I UBE2N UBE2T UBQLN2
Entrez ID		977	79589
HPRD ID		03763	02340
Ensembl ID		ENSG00000177697	ENSG00000133135
Uniprot IDs		A0A024RCB3 P48509 Q6ZNZ0	Q8TEB7
PDB IDs			3ICU
Enriched GO Terms of Interacting Partners?
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