CD151 and ITGA6

Data Source:
HPRD (in vivo)

		CD151	ITGA6
Description		CD151 molecule (Raph blood group)	integrin subunit alpha 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Basement Membrane Cytosol Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Cell Surface Membrane	Plasma Membrane Adherens Junction Focal Adhesion Cell Surface Filopodium Integrin Alpha6-beta4 Complex
	Molecular Function	Integrin Binding Protein Binding	Protein Binding Insulin-like Growth Factor I Binding Neuregulin Binding Laminin Binding Protein-containing Complex Binding Cadherin Binding Metal Ion Binding
	Biological Process	Cell Adhesion Viral Process Cell Migration Positive Regulation Of Cell Migration Hemidesmosome Assembly T Cell Proliferation Wound Healing, Spreading Of Cells Positive Regulation Of Endocytosis	Cell-substrate Junction Assembly Integrin-mediated Signaling Pathway Ectodermal Cell Differentiation Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Neuron Projection Development Extracellular Matrix Organization Positive Regulation Of Cell Migration Hemidesmosome Assembly Cell-substrate Adhesion Nail Development Positive Regulation Of Phosphorylation Positive Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Skin Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Leukocyte Migration Cellular Response To Organic Cyclic Compound Cell-cell Adhesion Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Assembly of collagen fibrils and other multimeric structures Type I hemidesmosome assembly	Assembly of collagen fibrils and other multimeric structures Basigin interactions Integrin cell surface interactions Integrin cell surface interactions Laminin interactions Laminin interactions Syndecan interactions Type I hemidesmosome assembly
Drugs
Diseases		Nephropathy with pretibial epidermolysis bullosa and deafness	Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA)
GWAS		Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494)	Alzheimer's disease biomarkers ( 23419831) Blood protein levels ( 28240269) Diabetic kidney disease ( 26305897) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Food allergy ( 29030101) Metabolite levels ( 23823483) Peanut allergy ( 29030101) Prostate cancer ( 31562322 19767753)
Interacting Genes		12 interacting genes: ARL13B BCL7A GRAMD1C ITGA3 ITGA6 ITGB1 KLRC1 MMP7 PTGFRN RNF128 TMEM139 TSPAN18	22 interacting genes: ADAM9 APP BIN1 CALM1 CANX CD151 CD36 CD63 CD82 COL17A1 GIPC1 GRB2 ITGB1 ITGB4 LGALS3BP PCSK5 PLEC PRKCD PXN RABIF RPSA TSPAN4
Entrez ID		977	3655
HPRD ID		03763	00945
Ensembl ID		ENSG00000177697	ENSG00000091409
Uniprot IDs		A0A024RCB3 P48509 Q6ZNZ0	P23229
PDB IDs
Enriched GO Terms of Interacting Partners?
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