RNF128 and CD151

Data Source:
HPRD (in vivo)

		RNF128	CD151
Description		ring finger protein 128	CD151 molecule (Raph blood group)
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Late Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Cytoskeleton Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Basement Membrane Cytosol Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Cell Surface Membrane
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Integrin Binding Protein Binding
	Biological Process	Negative Regulation Of Cytokine Production Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Deubiquitination Regulation Of Protein Stability Protein Localization To Lysosome Positive Regulation Of Protein Catabolic Process In The Vacuole	Cell Adhesion Viral Process Cell Migration Positive Regulation Of Cell Migration Hemidesmosome Assembly T Cell Proliferation Wound Healing, Spreading Of Cells Positive Regulation Of Endocytosis
Pathways		Ub-specific processing proteases Ovarian tumor domain proteases	Assembly of collagen fibrils and other multimeric structures Type I hemidesmosome assembly
Drugs
Diseases			Nephropathy with pretibial epidermolysis bullosa and deafness
GWAS		Alcoholic chronic pancreatitis ( 28754779) Creatinine levels ( 31015462) Estimated glomerular filtration rate ( 31015462)	Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494)
Interacting Genes		16 interacting genes: APPBP2 CD151 CD40LG CD81 CEP76 OTUB1 SNX17 TBK1 TP53 UBE2D1 UBE2E1 UBE2H UBE2I UBE2N UBE2T UBQLN2	12 interacting genes: ARL13B BCL7A GRAMD1C ITGA3 ITGA6 ITGB1 KLRC1 MMP7 PTGFRN RNF128 TMEM139 TSPAN18
Entrez ID		79589	977
HPRD ID		02340	03763
Ensembl ID		ENSG00000133135	ENSG00000177697
Uniprot IDs		Q8TEB7	A0A024RCB3 P48509 Q6ZNZ0
PDB IDs		3ICU
Enriched GO Terms of Interacting Partners?
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