RNF128 and UBE2T

Data Source:
BioGRID (two hybrid)

		RNF128	UBE2T
Description		ring finger protein 128	ubiquitin conjugating enzyme E2 T
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GO Annotations	Cellular Component	Cytoplasm Late Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Cytoskeleton Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Chromatin Binding Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Negative Regulation Of Cytokine Production Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Deubiquitination Regulation Of Protein Stability Protein Localization To Lysosome Positive Regulation Of Protein Catabolic Process In The Vacuole	Protein Polyubiquitination DNA Repair Protein Monoubiquitination Cellular Response To DNA Damage Stimulus Protein Ubiquitination Protein K29-linked Ubiquitination Interstrand Cross-link Repair Protein K27-linked Ubiquitination Protein Autoubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Protein K6-linked Ubiquitination
Pathways		Ub-specific processing proteases Ovarian tumor domain proteases	Fanconi Anemia Pathway Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Creatinine levels ( 31015462) Estimated glomerular filtration rate ( 31015462)	Breast cancer ( 23535733) Celiac disease ( 23936387)
Interacting Genes		16 interacting genes: APPBP2 CD151 CD40LG CD81 CEP76 OTUB1 SNX17 TBK1 TP53 UBE2D1 UBE2E1 UBE2H UBE2I UBE2N UBE2T UBQLN2	22 interacting genes: AMFR ARIH2 BRCA1 CDK2 CHEK1 FANCD2 FANCL LNX2 MARCHF5 MGRN1 PCGF2 PRKCG PRKN RNF128 RNF144B RNF31 RNF4 ROCK1 RPS6KA1 TRIM27 UBA1 UBA6
Entrez ID		79589	29089
HPRD ID		02340	13704
Ensembl ID		ENSG00000133135	ENSG00000077152
Uniprot IDs		Q8TEB7	A0A024R9A9 Q9NPD8
PDB IDs		3ICU	1YH2 4CCG 5NGZ 5OJJ 6R75
Enriched GO Terms of Interacting Partners?
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