GPRASP1 and OPRL1

Data Source:
BioGRID (pull down)

		GPRASP1	OPRL1
Description		G protein-coupled receptor associated sorting protein 1	opioid related nociceptin receptor 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Plasma Membrane Integral Component Of Plasma Membrane Cytoplasmic Vesicle Neuron Projection
	Molecular Function	Protein Binding	Nociceptin Receptor Activity G Protein-coupled Receptor Activity Protein Binding Peptide Binding Neuropeptide Binding
	Biological Process	Endosome To Lysosome Transport G Protein-coupled Receptor Catabolic Process	G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Sensory Perception Behavior Sensory Perception Of Pain Opioid Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway
Pathways			Peptide ligand-binding receptors G alpha (i) signalling events
Drugs			Buprenorphine Etorphine Epicept NP-1
Diseases
GWAS			Cerebrospinal AB1-42 levels in normal cognition ( 29274321) HDL cholesterol levels ( 32203549) LDL peak particle diameter (total fat intake interaction) ( 26112879) Lymphocyte counts ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Medication use (HMG CoA reductase inhibitors) ( 31015401) Metabolic syndrome ( 31589552) Monocyte count ( 32888494) Triglyceride levels ( 32203549 32154731)
Interacting Genes		47 interacting genes: ADRB1 ADRB2 AGTR1 ATXN7 C8orf33 CALCR CHRM1 CHRM2 CHRM3 CHRM4 CHRM5 CRIP1 CXCR2 F2R F2RL1 GLP1R GLYAT GRM1 GRM5 GRM8 HGH1 HMOX2 HTR7 LAMTOR5 LRP2 MAP7D1 MLNR MTF2 OFD1 OPRD1 OPRK1 OPRL1 OPRM1 OXTR PBK PER1 PFDN1 SNAPIN STMN2 TAC3 TACR1 TACR2 TACR3 TBXA2R TFG TRAF4 VIPR1	10 interacting genes: CERS6 DNAJC30 GNA14 GPRASP1 HLA-C OPRM1 PLLP PNOC RGS19 SLC31A2
Entrez ID		9737	4987
HPRD ID		02333	03971
Ensembl ID		ENSG00000198932	ENSG00000125510
Uniprot IDs		Q5JY77	A0A5F9ZI64 P41146 Q8IXB0
PDB IDs			4EA3 5DHG 5DHH
Enriched GO Terms of Interacting Partners?
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