GPRASP1 and HTR7

Data Source:
BioGRID (pull down)

		GPRASP1	HTR7
Description		G protein-coupled receptor associated sorting protein 1	5-hydroxytryptamine receptor 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Plasma Membrane Integral Component Of Plasma Membrane Dendrite Synapse
	Molecular Function	Protein Binding	G Protein-coupled Serotonin Receptor Activity Protein Binding Neurotransmitter Receptor Activity
	Biological Process	Endosome To Lysosome Transport G Protein-coupled Receptor Catabolic Process	Smooth Muscle Contraction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Circadian Rhythm Blood Circulation Vasoconstriction G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways			Serotonin receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs			Ziprasidone Methysergide Cabergoline Zolmitriptan Amitriptyline Clozapine Loxapine Cyproheptadine Imipramine Chlorpromazine Haloperidol Amoxapine Lisuride Paroxetine Risperidone Epinastine Cyclobenzaprine Maprotiline Dopamine Ergoloid mesylate Bromocriptine Quetiapine Aripiprazole Chlorprothixene Paliperidone Iloperidone Lofexidine Mianserin Asenapine Amisulpride Lurasidone Vortioxetine Zotepine Setiptiline Dihydroergocornine Gilteritinib Tiapride Dihydroergocristine SB-269970 Aripiprazole lauroxil
Diseases
GWAS			Alzheimer disease and age of onset ( 26830138) Liver fibrogenesis (alpha smooth muscle actin levels) ( 32953199) Midgestational total 25-hydroxyvitamin D levels (maternal genetic effect) ( 32047095) White matter microstructure (global fractional anisotropy) ( 24736177)
Interacting Genes		47 interacting genes: ADRB1 ADRB2 AGTR1 ATXN7 C8orf33 CALCR CHRM1 CHRM2 CHRM3 CHRM4 CHRM5 CRIP1 CXCR2 F2R F2RL1 GLP1R GLYAT GRM1 GRM5 GRM8 HGH1 HMOX2 HTR7 LAMTOR5 LRP2 MAP7D1 MLNR MTF2 OFD1 OPRD1 OPRK1 OPRL1 OPRM1 OXTR PBK PER1 PFDN1 SNAPIN STMN2 TAC3 TACR1 TACR2 TACR3 TBXA2R TFG TRAF4 VIPR1	2 interacting genes: GPRASP1 GPRASP2
Entrez ID		9737	3363
HPRD ID		02333	01639
Ensembl ID		ENSG00000198932	ENSG00000148680
Uniprot IDs		Q5JY77	P34969
PDB IDs
Enriched GO Terms of Interacting Partners?
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