CD68 and RALGDS

Data Source:
BioGRID (two hybrid)

		CD68	RALGDS
Description		CD68 molecule	ral guanine nucleotide dissociation stimulator
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Plasma Membrane Membrane Integral Component Of Membrane Late Endosome Membrane Azurophil Granule Membrane	Nucleus Cytosol Brush Border
	Molecular Function	Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding GTPase Regulator Activity
	Biological Process	Inflammatory Response To Antigenic Stimulus Negative Regulation Of Dendritic Cell Antigen Processing And Presentation Aging Cellular Response To Nutrient Levels Autocrine Signaling Neutrophil Degranulation Cellular Response To Lipopolysaccharide Establishment Of Protein Localization To Organelle Cellular Response To Oxidised Low-density Lipoprotein Particle Stimulus	Ras Protein Signal Transduction Regulation Of Catalytic Activity
Pathways		Neutrophil degranulation	p38MAPK events p38MAPK events RAF/MAP kinase cascade
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Heel bone mineral density ( 28869591) IgA levels ( 28628107) Metabolic syndrome ( 31589552) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278)	Blood protein levels in cardiovascular risk ( 28369058)
Interacting Genes		12 interacting genes: ADRB2 AGR2 AQP6 CLEC2D KTN1 MAL2 MUC1 PLEKHB2 RALGDS SGTB TMEM179B TOMM6	26 interacting genes: AFDN ARRB1 ARRB2 CD68 CNKSR1 CYSRT1 HOXA1 HRAS KRAS KRTAP10-8 LRPAP1 MAPK3 MRAS NF2 PDPK1 RAP1A RAP1B RAP1GAP RAP2A RAP2B RAPGEF2 RIN1 RIT1 RIT2 RRAS RRAS2
Entrez ID		968	5900
HPRD ID		01093	03371
Ensembl ID		ENSG00000129226	ENSG00000160271
Uniprot IDs		P34810	Q12967 Q8N4Y1
PDB IDs			1RAX 2B3A 2RGF 3KH0
Enriched GO Terms of Interacting Partners?
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