IPO13 and PPFIA2

Data Source:
BioGRID (affinity chromatography technology)

		IPO13	PPFIA2
Description		importin 13	PTPRF interacting protein alpha 2
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GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm Cytosol Cell Surface Axon Dendritic Spine Presynaptic Active Zone Extracellular Exosome Glutamatergic Synapse
	Molecular Function	Protein Binding	Protein Binding Structural Constituent Of Presynapse
	Biological Process	Protein Import Into Nucleus	Cell-matrix Adhesion Neurotransmitter Secretion Glutamate Secretion Synapse Organization Regulation Of Dendritic Spine Development Regulation Of Dendritic Spine Morphogenesis Presynapse Organization Dense Core Granule Cytoskeletal Transport Regulation Of Synaptic Vesicle Exocytosis
Pathways			Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Receptor-type tyrosine-protein phosphatases
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026)	Age-related cataracts (age at onset) ( 25352737) Alcohol dependence ( 26365420) Delirium ( 29631748) Lean body mass ( 28552196) Post bronchodilator FEV1 ( 26634245) Resting heart rate ( 27798624) Schizophrenia ( 22885689)
Interacting Genes		17 interacting genes: ALX1 CRX EIF1AX GK HMBOX1 MAGOH NPSR1 NUP50 PAX3 PAX6 PBX4 PITX1 PSMA1 RAN RBM8A RPL5 UBE2I	13 interacting genes: CAST CDC5L ERC2 GIT1 ITSN1 MTDH PPFIA1 PPFIA3 PPFIBP1 PPFIBP2 PTPRD PTPRF PTPRS
Entrez ID		9670	8499
HPRD ID		13742	04392
Ensembl ID		ENSG00000117408	ENSG00000139220
Uniprot IDs		O94829	B7Z7Y5 G3V200 H0YHK3 O75334 Q4LE62
PDB IDs		2X19 2XWU 3ZJY	3TAC 3TAD 6IUH
Enriched GO Terms of Interacting Partners?
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