PPFIA2 and PPFIBP2

Data Source:
HPRD (in vitro)

		PPFIA2	PPFIBP2
Description		PTPRF interacting protein alpha 2	PPFIA binding protein 2
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GO Annotations	Cellular Component	Cytoplasm Cytosol Cell Surface Axon Dendritic Spine Presynaptic Active Zone Extracellular Exosome Glutamatergic Synapse	Extracellular Space Cytosol Presynaptic Active Zone
	Molecular Function	Protein Binding Structural Constituent Of Presynapse	Molecular_function Protein Binding Identical Protein Binding
	Biological Process	Cell-matrix Adhesion Neurotransmitter Secretion Glutamate Secretion Synapse Organization Regulation Of Dendritic Spine Development Regulation Of Dendritic Spine Morphogenesis Presynapse Organization Dense Core Granule Cytoskeletal Transport Regulation Of Synaptic Vesicle Exocytosis	Neuromuscular Junction Development Synapse Organization
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Receptor-type tyrosine-protein phosphatases	Receptor-type tyrosine-protein phosphatases
Drugs
Diseases
GWAS		Age-related cataracts (age at onset) ( 25352737) Alcohol dependence ( 26365420) Delirium ( 29631748) Lean body mass ( 28552196) Post bronchodilator FEV1 ( 26634245) Resting heart rate ( 27798624) Schizophrenia ( 22885689)	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Blond vs. brown/black hair color ( 30531825) Brown vs. black hair color ( 30531825) Cutaneous melanoma or hair colour ( 32341527) Hair color ( 29662168) Malaria ( 31844061) Prostate cancer ( 29892016 26443449) Prostate cancer (advanced) ( 29892016)
Interacting Genes		13 interacting genes: CAST CDC5L ERC2 GIT1 ITSN1 MTDH PPFIA1 PPFIA3 PPFIBP1 PPFIBP2 PTPRD PTPRF PTPRS	12 interacting genes: APP CLK1 CRK CRKL DTNB HSF4 PPFIA1 PPFIA2 PPFIA3 PRNP PTPRC TSG101
Entrez ID		8499	8495
HPRD ID		04392	04391
Ensembl ID		ENSG00000139220	ENSG00000166387
Uniprot IDs		B7Z7Y5 G3V200 H0YHK3 O75334 Q4LE62	Q8ND30
PDB IDs		3TAC 3TAD 6IUH	3QH9
Enriched GO Terms of Interacting Partners?
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