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EIF1AX and IPO13
Data Source:
HPRD
(in vitro)
EIF1AX
IPO13
Description
eukaryotic translation initiation factor 1A X-linked
importin 13
Image
GO Annotations
Cellular Component
Cytosol
Nucleus
Cytoplasm
Molecular Function
RNA Binding
Translation Initiation Factor Activity
Protein Binding
Translation Factor Activity, RNA Binding
Protein Binding
Biological Process
Translational Initiation
Protein Import Into Nucleus
Pathways
L13a-mediated translational silencing of Ceruloplasmin expression
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Interacting Genes
9 interacting genes:
APP
EIF2S1
EIF3C
EIF5
EIF5B
HSPB1
IKBKG
IPO13
RFPL3
17 interacting genes:
ALX1
CRX
EIF1AX
GK
HMBOX1
MAGOH
NPSR1
NUP50
PAX3
PAX6
PBX4
PITX1
PSMA1
RAN
RBM8A
RPL5
UBE2I
Entrez ID
1964
9670
HPRD ID
02174
13742
Ensembl ID
ENSG00000173674
ENSG00000117408
Uniprot IDs
P47813
O94829
PDB IDs
1D7Q
3ZJY
4KZY
4KZZ
6YBW
6ZMW
6ZP4
7A09
2X19
2XWU
3ZJY
Enriched GO Terms of Interacting Partners
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