SCOC and TRAPPC6A

Data Source:
BioGRID (two hybrid)

		SCOC	TRAPPC6A
Description		short coiled-coil protein	trafficking protein particle complex subunit 6A
Image
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Endosome Golgi Apparatus Trans-Golgi Network Cytosol	Golgi Membrane Endoplasmic Reticulum Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Positive Regulation Of Macroautophagy Regulation Of Protein Complex Stability	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity COPII Vesicle Coating Melanosome Assembly
Pathways		Retrograde transport at the Trans-Golgi-Network	COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs			S-palmitoyl-L-cysteine
Diseases
GWAS		Malaria ( 31844061) Smoking status (ever vs never smokers) ( 30643258)	Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Cerebrospinal fluid AB1-42 levels ( 28247064)
Interacting Genes		16 interacting genes: ARL1 BFSP2 C21orf91 DDIT4L DOK5 FEZ1 FEZ2 ITSN1 KIFC3 KRT40 MAPK8 PSMC5 SCHIP1 SIKE1 TCF4 TRAPPC6A	47 interacting genes: BAG4 CAVIN2 CD2BP2 CRYAB CTDSP1 EFS EYA2 FOXN1 GGA3 GINS3 GOLGA6A GORASP2 HOXA1 HSPB8 IKZF3 INCA1 KANK4 KRTAP13-2 LHX4 MYOZ3 PAX6 PFDN5 PRR22 RAB3IP RAD54B REL RUSC1 SCOC SERTAD3 SF3B5 SMUG1 TAX1BP1 TEPSIN TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC3L TRAPPC6B TRIM35 TTC23 UBAP2 YPEL3 ZFP90 ZMIZ2 ZNRD2
Entrez ID		60592	79090
HPRD ID		18027	14503
Ensembl ID		ENSG00000153130	ENSG00000007255
Uniprot IDs		Q9UIL1	B7TZ90 O75865
PDB IDs		4BWD	2C0J 2J3T
Enriched GO Terms of Interacting Partners?
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