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CD53 and LAT
Data Source:
BioGRID
(two hybrid)
CD53
LAT
Description
CD53 molecule
linker for activation of T cells
Image
No pdb structure
GO Annotations
Cellular Component
Immunological Synapse
Plasma Membrane
Integral Component Of Plasma Membrane
Cell-cell Junction
Cell Surface
Specific Granule Membrane
Extracellular Exosome
Tertiary Granule Membrane
Immunological Synapse
Golgi Apparatus
Plasma Membrane
COP9 Signalosome
Integral Component Of Membrane
Membrane Raft
Molecular Function
Protein Binding
Identical Protein Binding
Protein Binding
Protein Kinase Binding
Signaling Receptor Complex Adaptor Activity
Biological Process
Signal Transduction
Neutrophil Degranulation
Positive Regulation Of Myoblast Fusion
MAPK Cascade
Adaptive Immune Response
Inflammatory Response
Immune Response
Integrin-mediated Signaling Pathway
Ras Protein Signal Transduction
Calcium-mediated Signaling
Intracellular Signal Transduction
Fc-epsilon Receptor Signaling Pathway
T Cell Activation
Mast Cell Degranulation
Positive Regulation Of Protein Kinase Activity
T Cell Receptor Signaling Pathway
Regulation Of T Cell Activation
Pathways
Neutrophil degranulation
GPVI-mediated activation cascade
Generation of second messenger molecules
Drugs
Diseases
GWAS
Cytomegalovirus antibody response (
21993531
)
Obesity-related traits (
23251661
)
Allergic disease (asthma, hay fever or eczema) (
29679657
)
Crohn's disease (
21102463
)
Educational attainment (
25201988
)
Interacting Genes
80 interacting genes:
AIG1
APOD
ARL13B
ASGR2
ATP6V0C
BCL2L13
BIK
BTN2A2
C1QL4
CD2
CD302
CD37
CD4
CD9
CLCN7
CLDN19
CLDN7
CLEC7A
CNIH1
CNIH2
COL4A5
CREB3L1
CTXN3
CXCL16
CYBC1
ECE2
EFNA5
EMP1
ERG28
FAM209A
GET1
GGT1
GIMAP5
GJA8
GPR108
GPR152
GPX8
IFITM3
IGFBP5
IL2
IL4
KIR3DL3
LAT
LHFPL5
LPAR3
LSMEM1
MAL
MS4A3
MUC1
NKG7
PLN
PLP2
PMP22
PSCA
RPRM
SAR1A
SERTM1
SLC35A1
SLC7A14
SMAGP
SMIM3
SNORC
ST6GAL2
STRIT1
STX2
TMEM128
TMEM140
TMEM218
TMEM229B
TMEM237
TMEM60
TMEM86B
TMEM97
TRAM1L1
TRARG1
TSPO2
UBIAD1
UPK1B
VAMP5
VSTM1
95 interacting genes:
APH1A
ASGR2
BCL2L13
BSCL2
CAMLG
CBL
CD244
CD3G
CD4
CD53
CD8A
CDIP1
CLDN2
CLDN5
CLDN7
CREB3
CXorf66
CYBC1
EGFR
FCGR1A
FCGR2A
FFAR2
FFAR3
FKBP7
FYN
GAB2
GJA8
GJB1
GJB3
GOLM1
GPR101
GPR151
GPR152
GPR42
GRAP
GRAP2
GRB2
ITK
JSRP1
KASH5
KCTD17
KIR2DL3
LCK
LCP2
LEUTX
LHFPL1
LHFPL5
LMNA
MAP1LC3C
MAP4K1
MEOX2
MFF
MFSD14B
MFSD5
MRPS18B
MS4A7
MTIF3
NDUFAF2
OPRM1
PIK3R1
PLCG1
PLCG2
PRR4
PSCA
PTPN1
PTPN6
PTPRJ
SAR1A
SERINC2
SGTA
SGTB
SH3BP2
SHB
SLA
SLC14A2
SLC16A2
SLC18A1
SLC19A3
SLC26A6
SLC35C2
SLC51B
SLPI
SSMEM1
SYK
SYT2
THAP4
TM4SF18
TMEM237
TMEM45B
TMEM80
TNFRSF10D
VAV1
ZAP70
ZDHHC7
ZHX2
Entrez ID
963
27040
HPRD ID
01054
03832
Ensembl ID
ENSG00000143119
ENSG00000213658
Uniprot IDs
B4DQB5
P19397
A0A024QZD6
O43561
PDB IDs
6WVG
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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