CD53 and CNIH2

Data Source:
BioGRID (two hybrid)

		CD53	CNIH2
Description		CD53 molecule	cornichon family AMPA receptor auxiliary protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Cell Surface Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane	Golgi Membrane Endoplasmic Reticulum Membrane ER To Golgi Transport Vesicle Membrane Postsynaptic Density Dendrite AMPA Glutamate Receptor Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Dendritic Spine Dendritic Shaft Synapse Postsynaptic Membrane Glutamatergic Synapse Integral Component Of Postsynaptic Density Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Signal Transduction Neutrophil Degranulation Positive Regulation Of Myoblast Fusion	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Synaptic Transmission, Glutamatergic Regulation Of Membrane Potential COPII Vesicle Coating Localization Within Membrane Regulation Of Postsynaptic Neurotransmitter Receptor Activity Negative Regulation Of Receptor Localization To Synapse Negative Regulation Of Anterograde Synaptic Vesicle Transport Regulation Of NMDA Receptor Activity Regulation Of AMPA Receptor Activity
Pathways		Neutrophil degranulation	COPII-mediated vesicle transport Cargo concentration in the ER
Drugs
Diseases
GWAS		Cytomegalovirus antibody response ( 21993531) Obesity-related traits ( 23251661)	Bipolar disorder ( 21926972 31043756) Insomnia ( 32332799) Urate levels ( 31578528)
Interacting Genes		80 interacting genes: AIG1 APOD ARL13B ASGR2 ATP6V0C BCL2L13 BIK BTN2A2 C1QL4 CD2 CD302 CD37 CD4 CD9 CLCN7 CLDN19 CLDN7 CLEC7A CNIH1 CNIH2 COL4A5 CREB3L1 CTXN3 CXCL16 CYBC1 ECE2 EFNA5 EMP1 ERG28 FAM209A GET1 GGT1 GIMAP5 GJA8 GPR108 GPR152 GPX8 IFITM3 IGFBP5 IL2 IL4 KIR3DL3 LAT LHFPL5 LPAR3 LSMEM1 MAL MS4A3 MUC1 NKG7 PLN PLP2 PMP22 PSCA RPRM SAR1A SERTM1 SLC35A1 SLC7A14 SMAGP SMIM3 SNORC ST6GAL2 STRIT1 STX2 TMEM128 TMEM140 TMEM218 TMEM229B TMEM237 TMEM60 TMEM86B TMEM97 TRAM1L1 TRARG1 TSPO2 UBIAD1 UPK1B VAMP5 VSTM1	6 interacting genes: CD53 CREB3L1 GORAB HIBADH TMEM14B TMPRSS2
Entrez ID		963	254263
HPRD ID		01054	13078
Ensembl ID		ENSG00000143119	ENSG00000174871
Uniprot IDs		B4DQB5 P19397	Q6PI25
PDB IDs		6WVG
Enriched GO Terms of Interacting Partners?
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