MVB12A and OXTR

Data Source:
BioGRID (two hybrid)

		MVB12A	OXTR
Description		multivesicular body subunit 12A	oxytocin receptor
Image
GO Annotations	Cellular Component	ESCRT I Complex Nucleoplasm Golgi Apparatus Centrosome Cytosol Endosome Membrane Late Endosome Membrane Vesicle Host Cell Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Microvillus Adherens Junction Apical Plasma Membrane
	Molecular Function	Protein Binding Lipid Binding SH3 Domain Binding Ubiquitin Binding	G Protein-coupled Receptor Activity Oxytocin Receptor Activity Vasopressin Receptor Activity Peptide Hormone Binding Peptide Binding
	Biological Process	Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Virus Maturation Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Receptor Catabolic Process Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Budding Intracellular Transport Of Virus	Suckling Behavior Response To Amphetamine Regulation Of Systemic Arterial Blood Pressure By Vasopressin Muscle Contraction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Heart Development Female Pregnancy Lactation Memory Positive Regulation Of Norepinephrine Secretion Telencephalon Development Sleep Positive Regulation Of Synaptic Transmission, GABAergic Response To Estradiol Response To Progesterone Response To Anoxia Response To Cytokine Social Behavior Response To Cocaine Response To Drug Maternal Behavior Sperm Ejaculation Eating Behavior Response To Peptide Hormone Estrous Cycle Positive Regulation Of Blood Pressure Positive Regulation Of Vasoconstriction Digestive Tract Development Positive Regulation Of Synapse Assembly Positive Regulation Of Synaptic Transmission, Glutamatergic Maternal Process Involved In Parturition Positive Regulation Of Penile Erection Negative Regulation Of Gastric Acid Secretion ERK1 And ERK2 Cascade Positive Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Cold-induced Thermogenesis
Pathways		Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy	Vasopressin-like receptors G alpha (q) signalling events
Drugs			Oxytocin Carbetocin Atosiban Relcovaptan
Diseases
GWAS			Caudate activity during reward ( 28927378) Chronotype ( 30696823) Depression and alcohol dependence ( 22064162) Liver fibrosis severity in HIV/hepatitis C co-infection ( 27339598) Morning person ( 30696823)
Interacting Genes		6 interacting genes: APP CD2AP HSF2BP OXTR PPP1R27 SH3KBP1	18 interacting genes: ALAS1 ARRB2 ASH1L AVP CD81 CYFIP2 EMC10 FSCN1 GPRASP1 LCNL1 MVB12A OXT PSMA7 SIRT2 THOC5 TMEM161A TSPAN7 YIPF3
Entrez ID		93343	5021
HPRD ID		14298	01328
Ensembl ID		ENSG00000141971	ENSG00000180914
Uniprot IDs		A0A024R7L6 Q96EY5	B2R9L7 P30559
PDB IDs		6VME	6TPK
Enriched GO Terms of Interacting Partners?
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