MVB12A and PPP1R27

Data Source:
BioGRID (two hybrid)

		MVB12A	PPP1R27
Description		multivesicular body subunit 12A	protein phosphatase 1 regulatory subunit 27
Image			No pdb structure
GO Annotations	Cellular Component	ESCRT I Complex Nucleoplasm Golgi Apparatus Centrosome Cytosol Endosome Membrane Late Endosome Membrane Vesicle Host Cell Extracellular Exosome
	Molecular Function	Protein Binding Lipid Binding SH3 Domain Binding Ubiquitin Binding	Protein Phosphatase Inhibitor Activity Protein Binding Phosphatase Binding
	Biological Process	Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Virus Maturation Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Receptor Catabolic Process Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Budding Intracellular Transport Of Virus	Negative Regulation Of Phosphatase Activity Negative Regulation Of Phosphoprotein Phosphatase Activity
Pathways		Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS
Interacting Genes		6 interacting genes: APP CD2AP HSF2BP OXTR PPP1R27 SH3KBP1	9 interacting genes: DDIT4L GCC1 KRT34 MVB12A NTAQ1 PPP1CA PPP1CB RPL9 SMCP
Entrez ID		93343	116729
HPRD ID		14298	17334
Ensembl ID		ENSG00000141971	ENSG00000182676
Uniprot IDs		A0A024R7L6 Q96EY5	Q86WC6
PDB IDs		6VME
Enriched GO Terms of Interacting Partners?
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