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OXTR and SIRT2
Data Source:
BioGRID
(two hybrid)
OXTR
SIRT2
Description
oxytocin receptor
sirtuin 2
Image
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Microvillus
Adherens Junction
Apical Plasma Membrane
Chromosome, Telomeric Region
Heterochromatin
Nucleus
Chromatin Silencing Complex
Chromosome
Nucleolus
Cytoplasm
Mitochondrion
Centrosome
Centriole
Spindle
Cytosol
Microtubule
Plasma Membrane
Growth Cone
Midbody
Paranodal Junction
Paranode Region Of Axon
Perikaryon
Myelin Sheath
Lateral Loop
Schmidt-Lanterman Incisure
Juxtaparanode Region Of Axon
Perinuclear Region Of Cytoplasm
Mitotic Spindle
Meiotic Spindle
Glial Cell Projection
Molecular Function
G Protein-coupled Receptor Activity
Oxytocin Receptor Activity
Vasopressin Receptor Activity
Peptide Hormone Binding
Peptide Binding
Chromatin Binding
NAD+ ADP-ribosyltransferase Activity
Histone Deacetylase Activity
Protein Binding
Transcription Factor Binding
Zinc Ion Binding
NAD-dependent Histone Deacetylase Activity
Protein Deacetylase Activity
NAD-dependent Protein Deacetylase Activity
Histone Acetyltransferase Binding
Histone Deacetylase Binding
Tubulin Deacetylase Activity
Ubiquitin Binding
NAD-dependent Histone Deacetylase Activity (H4-K16 Specific)
NAD+ Binding
Biological Process
Suckling Behavior
Response To Amphetamine
Regulation Of Systemic Arterial Blood Pressure By Vasopressin
Muscle Contraction
Cell Surface Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Heart Development
Female Pregnancy
Lactation
Memory
Positive Regulation Of Norepinephrine Secretion
Telencephalon Development
Sleep
Positive Regulation Of Synaptic Transmission, GABAergic
Response To Estradiol
Response To Progesterone
Response To Anoxia
Response To Cytokine
Social Behavior
Response To Cocaine
Response To Drug
Maternal Behavior
Sperm Ejaculation
Eating Behavior
Response To Peptide Hormone
Estrous Cycle
Positive Regulation Of Blood Pressure
Positive Regulation Of Vasoconstriction
Digestive Tract Development
Positive Regulation Of Synapse Assembly
Positive Regulation Of Synaptic Transmission, Glutamatergic
Maternal Process Involved In Parturition
Positive Regulation Of Penile Erection
Negative Regulation Of Gastric Acid Secretion
ERK1 And ERK2 Cascade
Positive Regulation Of Uterine Smooth Muscle Contraction
Positive Regulation Of Cold-induced Thermogenesis
Negative Regulation Of Transcription By RNA Polymerase II
RDNA Heterochromatin Assembly
Chromatin Silencing
Chromatin Silencing At Telomere
Protein ADP-ribosylation
Protein Deacetylation
Autophagy
Regulation Of Exit From Mitosis
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Autophagy
Negative Regulation Of Peptidyl-threonine Phosphorylation
Phosphatidylinositol 3-kinase Signaling
Histone Deacetylation
Substantia Nigra Development
Myelination In Peripheral Nervous System
Regulation Of Myelination
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Oxidative Stress
Peptidyl-lysine Deacetylation
Cellular Response To Hepatocyte Growth Factor Stimulus
Negative Regulation Of Protein Catabolic Process
Regulation Of Phosphorylation
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of DNA Binding
Protein Kinase B Signaling
Cellular Lipid Catabolic Process
Innate Immune Response
Negative Regulation Of Fat Cell Differentiation
Positive Regulation Of Meiotic Nuclear Division
Negative Regulation Of Striated Muscle Tissue Development
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Hepatocyte Growth Factor Receptor Signaling Pathway
Cell Division
Meiotic Cell Cycle
Regulation Of Cell Cycle
Response To Redox State
Positive Regulation Of Cell Division
Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Cellular Response To Caloric Restriction
Negative Regulation Of Oligodendrocyte Progenitor Proliferation
Histone H3 Deacetylation
Histone H4 Deacetylation
Cellular Response To Molecule Of Bacterial Origin
Cellular Response To Hypoxia
Cellular Response To Epinephrine Stimulus
Tubulin Deacetylation
Positive Regulation Of Execution Phase Of Apoptosis
Positive Regulation Of Oocyte Maturation
Negative Regulation Of NLRP3 Inflammasome Complex Assembly
Negative Regulation Of Defense Response To Bacterium
Negative Regulation Of Reactive Oxygen Species Metabolic Process
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Involved In Cellular Response To Hypoxia
Pathways
Vasopressin-like receptors
G alpha (q) signalling events
Initiation of Nuclear Envelope (NE) Reformation
Drugs
Oxytocin
Carbetocin
Atosiban
Relcovaptan
Cambinol
Diseases
GWAS
Caudate activity during reward (
28927378
)
Chronotype (
30696823
)
Depression and alcohol dependence (
22064162
)
Liver fibrosis severity in HIV/hepatitis C co-infection (
27339598
)
Morning person (
30696823
)
Interacting Genes
18 interacting genes:
ALAS1
ARRB2
ASH1L
AVP
CD81
CYFIP2
EMC10
FSCN1
GPRASP1
LCNL1
MVB12A
OXT
PSMA7
SIRT2
THOC5
TMEM161A
TSPAN7
YIPF3
19 interacting genes:
ARHGDIA
CDC14B
CDC20
CDK2
EP300
FZR1
H3C1
HDAC6
HIF1A
HOXA10
KAT2A
KAT2B
MDM2
OXTR
PLA2G4A
RAD51
SP140
TUBA4A
XPO1
Entrez ID
5021
22933
HPRD ID
01328
10377
Ensembl ID
ENSG00000180914
ENSG00000068903
Uniprot IDs
B2R9L7
P30559
A0A024R0G8
A0A0A0MRF5
Q8IXJ6
PDB IDs
6TPK
1J8F
3ZGO
3ZGV
4L3O
4R8M
4RMG
4RMH
4RMI
4RMJ
4X3O
4X3P
4Y6L
4Y6O
4Y6Q
5D7O
5D7P
5D7Q
5DY4
5DY5
5FYQ
5G4C
5MAR
5MAT
5Y0Z
5Y5N
5YQL
5YQM
5YQN
5YQO
6L65
6L66
6NR0
6QCN
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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