ATP6V0B and GPR61

Data Source:
BioGRID (two hybrid)

		ATP6V0B	GPR61
Description		ATPase H+ transporting V0 subunit b	G protein-coupled receptor 61
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Vacuolar Membrane Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain	Endosome Plasma Membrane Endosome Membrane Integral Component Of Membrane Receptor Complex
	Molecular Function	Transporter Activity Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism	G Protein-coupled Receptor Activity Protein Binding Arrestin Family Protein Binding
	Biological Process	Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport	G Protein-coupled Receptor Signaling Pathway Positive Regulation Of CAMP-mediated Signaling
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Tiludronic acid
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026)	Adult body size ( 32376654) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body size at age 10 ( 32376654) Childhood body mass index ( 26604143) Chronotype ( 30696823) Hepcidin/ferritin ratio ( 27846281) Morning person ( 30696823) Stearic acid (18:0) levels ( 23362303) Waist circumference ( 25673412)
Interacting Genes		28 interacting genes: ADGRG3 ADRB2 APOD COL4A5 EMP1 FAM210B FAS GJA8 GPR42 GPR61 INSIG2 IRAK3 KLRC1 MFF MIP MS4A3 MTNR1B NRM SLC10A1 SLC2A5 SNTA1 SPACA1 STOM TM4SF19 TMEM242 VMA21 YWHAE YWHAG	20 interacting genes: APP ARL6IP6 ATP6V0B C4orf3 CLDND1 CTXN3 EMP3 FCER1G GJA8 GJB6 KLRC1 PLP1 PMP22 SCN3B SLC12A7 SLC13A4 STRIT1 TMEM147 TMEM218 TRARG1
Entrez ID		533	83873
HPRD ID		04759	06077
Ensembl ID		ENSG00000117410	ENSG00000156097
Uniprot IDs		E9PNL3 Q99437	G4XH66 Q9BZJ8
PDB IDs
Enriched GO Terms of Interacting Partners?
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