ATP6V0B and ADGRG3

Data Source:
BioGRID (two hybrid)

		ATP6V0B	ADGRG3
Description		ATPase H+ transporting V0 subunit b	adhesion G protein-coupled receptor G3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Vacuolar Membrane Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Specific Granule Membrane
	Molecular Function	Transporter Activity Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism	G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport	Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway B Cell Differentiation Regulation Of Cell Migration Negative Regulation Of CREB Transcription Factor Activity Neutrophil Degranulation Negative Regulation Of NIK/NF-kappaB Signaling
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	Neutrophil degranulation
Drugs		Tiludronic acid
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		28 interacting genes: ADGRG3 ADRB2 APOD COL4A5 EMP1 FAM210B FAS GJA8 GPR42 GPR61 INSIG2 IRAK3 KLRC1 MFF MIP MS4A3 MTNR1B NRM SLC10A1 SLC2A5 SNTA1 SPACA1 STOM TM4SF19 TMEM242 VMA21 YWHAE YWHAG	12 interacting genes: ATP6V0B C3orf52 C4orf3 CTXN3 GIMAP5 LHFPL5 PLP1 RPRM SEC22A TEX264 UPK2 VSTM1
Entrez ID		533	222487
HPRD ID		04759	17073
Ensembl ID		ENSG00000117410	ENSG00000182885
Uniprot IDs		E9PNL3 Q99437	B4DVW2 F8W8F7 Q86Y34
PDB IDs
Enriched GO Terms of Interacting Partners?
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