CDKN3 and MS4A3

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid, in vivo)

		CDKN3	MS4A3
Description		cyclin dependent kinase inhibitor 3	membrane spanning 4-domains A3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Perinuclear Region Of Cytoplasm	Plasma Membrane Integral Component Of Membrane Specific Granule Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Protein Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G1/S Transition Of Mitotic Cell Cycle Cell Cycle Arrest Negative Regulation Of Cell Population Proliferation Peptidyl-tyrosine Dephosphorylation	Neutrophil Degranulation Regulation Of Cell Cycle
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Dental caries ( 23259602) Endometrial cancer (Non-endometrioid histology) ( 30093612) High myopia ( 31816047) Metabolite levels ( 23823483) Metabolite levels (X-11787) ( 23934736) Monobrow thickness ( 26926045) Myopia ( 27182965) Refractive error ( 32231278) Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309)	Alzheimer's disease ( 24755620) Vitamin B12 levels ( 22367966)
Interacting Genes		9 interacting genes: CDC25A CDK1 CDK2 CDK3 CEBPA MS4A3 NCOA3 PPP1R12A ROCK2	38 interacting genes: ADIPOQ ATP6V0B BMP10 BNIP3 C4orf3 CCDC167 CD53 CD72 CDKN3 CLDN1 CLDN6 EFNA5 EMP3 ERG28 IFITM3 IGFBP5 MS4A13 NKG7 PLP1 PLPP6 SEC22A SGTA SLC22A14 SLC5A4 SMCO4 SMIM3 STX8 TEX264 TM4SF18 TMBIM6 TMEM107 TMEM140 TMEM182 TMEM218 TMEM239 VKORC1L1 YIPF6 ZFPL1
Entrez ID		1033	932
HPRD ID		00450	09403
Ensembl ID		ENSG00000100526	ENSG00000149516
Uniprot IDs		G3V2J7 Q16667	Q96HJ5
PDB IDs		1FPZ 1FQ1
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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