CDKN3 and CDK3

Data Source:
HPRD (two hybrid, in vivo)

		CDKN3	CDK3
Description		cyclin dependent kinase inhibitor 3	cyclin dependent kinase 3
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GO Annotations	Cellular Component	Cytoplasm Cytosol Perinuclear Region Of Cytoplasm	Nucleus
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G1/S Transition Of Mitotic Cell Cycle Cell Cycle Arrest Negative Regulation Of Cell Population Proliferation Peptidyl-tyrosine Dephosphorylation	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Cellular Response To DNA Damage Stimulus Cell Population Proliferation G0 To G1 Transition Cell Division Regulation Of Cell Cycle
Pathways
Drugs
Diseases
GWAS		Dental caries ( 23259602) Endometrial cancer (Non-endometrioid histology) ( 30093612) High myopia ( 31816047) Metabolite levels ( 23823483) Metabolite levels (X-11787) ( 23934736) Monobrow thickness ( 26926045) Myopia ( 27182965) Refractive error ( 32231278) Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309)
Interacting Genes		9 interacting genes: CDC25A CDK1 CDK2 CDK3 CEBPA MS4A3 NCOA3 PPP1R12A ROCK2	39 interacting genes: APP CABLES1 CABLES2 CCNA2 CCNC CCND3 CCNE1 CCNE2 CCNH CCNI CDC37 CDKN1A CDKN1B CDKN3 CKS1B CKS2 E2F1 E2F2 E2F3 FOXP2 FRS2 KIR3DL1 LHX3 LHX4 MEOX2 NEDD4L NELFA OR2G6 OTX2 PAX5 PAX6 PAX8 PPARA RACGAP1 RB1 SPDYE4 STN1 TRIM55 TRIM63
Entrez ID		1033	1018
HPRD ID		00450	00446
Ensembl ID		ENSG00000100526	ENSG00000250506
Uniprot IDs		G3V2J7 Q16667	Q00526
PDB IDs		1FPZ 1FQ1	1LFN
Enriched GO Terms of Interacting Partners?
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